105878-79-3

Basic information

• Product Name: Benzoic acid, 3-chloro-5-[7-[4-(2,2-dimethyl-1-oxopropoxy)-2,5-dihydro-5,5-dimethyl-2 -furanyl]-3-methyl-2,6-octadienyl]-4,6-dimethoxy-2-methyl-, methyl ester, (E,E)-
• CAS NO: 105878-79-3
• Molecular Formula: C31H43ClO7
• Molecular Weight: 563.131
• Mol File: 105878-79-3.mol

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 3-chloro-5-[7-[4-(2,2-dimethyl-1-oxopropoxy)-2,5-dihydro-5,5-dimethyl-2 -furanyl]-3-methyl-2,6-octadienyl]-4,6-dimethoxy-2-methyl-, methyl ester, (E,E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 3-chloro-5-[7-[4-(2,2-dimethyl-1-oxopropoxy)-2,5-dihydro-5,5-dimethyl-2 -furanyl]-3-methyl-2,6-octadienyl]-4,6-dimethoxy-2-methyl-, methyl ester, (E,E)-(105878-79-3)
• EPA Substance Registry System: Benzoic acid, 3-chloro-5-[7-[4-(2,2-dimethyl-1-oxopropoxy)-2,5-dihydro-5,5-dimethyl-2 -furanyl]-3-methyl-2,6-octadienyl]-4,6-dimethoxy-2-methyl-, methyl ester, (E,E)-(105878-79-3)

Safety Data

• Hazardous Substances Data: 105878-79-3(Hazardous Substances Data)

Upstream product

• 102227-58-7 (E,E)-2,6,10-trimethyl-12-(tetrahydropyran-2-yloxy)dodeca-6,10-dien-3-yne-2,5-diol 
• 115-19-5 2-methyl-but-3-yn-2-ol 
• 107669-74-9 (E,E)-2,6,10-trimethyl-5-pivaloyloxy-12-(tetrahydropyran-2-yloxy)dodeca-6,10-dien-3-yn-2-ol 
• 107669-75-0 5-<(E,E)-1,5-dimethyl-7-(tetrahydropyran-2-yloxy)hepta-1,5-dienyl>-2,2-dimethyl-3-pivaloyloxy-2,5-dihydrofuran 
• 109625-61-8 5-<(E,E)-7-hydroxy-1,5-dimethylhepta-1,5-dienyl>-2,2-dimethyl-3-pivaloyloxy-2,5-dihydrofuran 
• 3282-30-2 pivaloyl chloride 
• 105427-89-2 methyl 3-bromo-5-chloro-2,4-dimethoxy-6-methylbenzoate 
• 105878-81-7 5-<(E,E)-7-bromo-1,5-dimethylhepta-1,5-dienyl>-2,2-dimethyl-3-pivaloyloxy-2,5-dihydrofuran 

Downstream Products

• 105929-14-4 3-chloro-4,6-dimethoxy-2-methyl-5-<(E,E)-3-methyl-7-(tetrahydro-5,5-dimethyl-4-oxofuran-2-yl)octa-2,6-dienyl>benzaldehyde 

Relevant articles and documents

Total synthesis of dl-ascofuranone and related compounds

Convergent synthesis of an antitumor protective agent, ascofuranone, was accomplished by (1) preparation of the terpenoid side chain having a furanone moiety, (2) coupling the side chain with a protected phenol derivative, and (3) deprotection to regenerate the hydroxyl groups. This strategy was successfully applied to the synthesis of oxidized and cyclized analogs of ascofuranone. Some of the ascofuranone derivatives were found to inhibit the growth of P388 leukemia cells.