1059192-32-3Relevant academic research and scientific papers
Copper-catalyzed aerobic aliphatic C-H oxygenation directed by an amidine moiety
Wang, Yi-Feng,Chen, Hui,Zhu, Xu,Chiba, Shunsuke
, p. 11980 - 11983 (2012/09/08)
A method for the oxygenation of tertiary C-H bonds of N-alkylamidines and N-(2-alkylaryl)amidines is described that utilizes the CuBr?SMe 2/2,2′-bipyridine catalytic system under an O2 atmosphere and provides dihydrooxazoles and 4H-1,3-benzoxazines. The oxygen atom is incorporated from atmospheric molecular oxygen during the present process.
Conformationally constrained adamantaneoxazolines of pharmacological interest
Papanastasiou, Ioannis,Foscolos, George B.,Tsotinis, Andrew,Olah, Judit,Ovadi, Judit,Radhika Prathalingam,Kelly, John M.
experimental part, p. 2043 - 2061 (2009/04/06)
New conformationally constrained adamantane 2-oxazoline building blocks 1-4 were synthesized and their antimicrotubule and antitrypanosomal potency was investigated. Although most of the new compounds affect tubulin polymerization, this does not make a major contribution to trypanocidal activity.
