10596-19-7Relevant academic research and scientific papers
Water enhanced synthesis of gem-bisphosphonates via Rh(i) mediated 1,4-conjugate addition of aryl boronic acids to vinylidenebisphosphonate esters
Bianchini, Giulio,Scarso, Alessandro,Chiminazzo, Andrea,Sperni, Laura,Strukul, Giorgio
supporting information, p. 656 - 662 (2013/03/29)
A new synthetic method characterized by low environmental impact for the synthesis of a wide range of gem-bisphosphonates bearing aryl substituents in β position as potential anti-resorption species to contrast osteoporosis is reported. The pivotal role p
gem-Diphosphonate and gem-phosphonate-phosphate compounds with specific high density lipoprotein inducing activity
Nguyen,Niesor,Bentzen
, p. 1426 - 1433 (2007/10/02)
New diphosphonate compounds and related derivatives were synthesized and investigated for their activity in specifically inducing plasma high density lipoproteins (HDL) and high density lipoprotein cholesterol (HDL-C) in normal rats. The screening of nume
