10596-47-1

Upstream product

• 2403-55-6 4-(2-methyl-1-propenyl)morpholine 
• 536-74-3 phenylacetylene 
• 110-91-8 morpholine 
• 78-84-2 isobutyraldehyde 
• 637-44-5 phenylpropyolic acid 

Downstream Products

• 3160-32-5 (1E)-4-methyl-1-phenylpent-1-en-3-one 

Relevant academic research and scientific papers

Cu0NPs@CMC: an efficient recoverable nanocatalyst for decarboxylative A3 and A3 couplings under neat condition

Abstract: Copper nanoparticles assembled on carboxymethylcellulose (Cu0NPs@CMC) were successfully synthesized and well characterized by FT-IR, SEM, EDS, TEM, XPS, and ICP-AES. The new prepared nanocatalyst was applied effectively as a heterogen

Nano magnetite supported metal ions as robust, efficient and recyclable catalysts for green synthesis of propargylamines and 1,4-disubstituted 1,2,3-triazoles in water

Nano magnetite functionalized 2,2′-biimidazole complex of metal ions Cu(i), Cu(ii), Ni(ii) and Co(ii) were successfully synthesized and characterized by different techniques such as elemental analysis, FT-IR spectroscopy, X-ray diffraction (XRD), thermo gravimetric analysis (TGA), transmission electron microscopy (TEM), scanning electron microscopy with energy dispersive X-ray spectroscopy (SEM with EDS), atomic absorption spectroscopy (AAS), inductively coupled plasma-optical emission spectrometry (ICP-OES) and vibrating sample magnetometer (VSM) instrument. The synthesized magnetic nanoparticles were used as heterogeneous catalysts for the synthesis of propargylamines via the three-component coupling reaction of aldehydes, alkynes and amines and one-pot synthesis of 1,4-disubstituted 1,2,3-triazoles by the click reaction of primary halides or tosylates, sodium azide and terminal acetylenes in aqueous media. The prepared nanocatalyst can be facilely recovered and reused many times without a significant decrease in activity and selectivity. The high catalytic activity, thermal stability and reusability, simple recovery and eco-friendly nature of the catalyst make the present method particularly attractive in green chemistry.

Magnetic CuO nanoparticles supported on graphene oxide as an efficient catalyst for A3-coupling synthesis of propargylamines

Magnetically separable CuO nanoparticles supported on graphene oxide (Fe3O4 NPs/GO-CuO NPs) is synthesized and characterized for the preparation of propargylamines in EtOH, at 90 °C. Fe3O4 NPs/GO-CuO NPs is foun

Manganese(ii) chloride catalyzed highly efficient one-pot synthesis of propargylamines and fused triazoles via three-component coupling reaction under solvent-free condition

A one-pot green and highly efficient method for the synthesis of propargylamines and diastereoselective synthesis of fused triazoles via three-component coupling in the presence of manganese(ii) chloride as a catalyst and a catalyst-free 1,3-dipolar cycloaddition reaction, respectively, without using a co-catalyst or activator is reported. This methodology is efficient, eco-friendly, operationally simple and effective for reactions involving aromatic, aliphatic, and heterocyclic aldehydes, and provides an easy access to propargylamines in excellent yields, fused triazoles in good yield and excellent diastereoselectivities.

Cu(II) salen complex catalyzed synthesis of propargylamines by a three-component coupling reaction

A one pot three-component coupling reaction of phenylacetylene, aldehyde, and amine derivatives in the presence of Cu(II) Salen complex as an efficient heterogeneous catalyst under solvent-free conditions is reported. The catalyst displayed high activity

Postsynthetic modification of metal-organic framework as a highly efficient and recyclable catalyst for three-component (aldehyde-alkyne-amine) coupling reaction

A MOF-supported Cu(I) catalyst bearing N,O-chelating ligand was prepared through postsynthetic modification of IRMOF-3 and used as an efficient heterogeneous catalyst for three-component coupling reaction of aldehyde, alkyne, and amine. The catalyst exhib

Fe3O4 nanoparticles: A robust and magnetically recoverable catalyst for three-component coupling of aldehyde, alkyne and amine

A robust, safe and magnetically recoverable Fe3O4 nanoparticle catalyzed three-component coupling of aldehyde, alkyne, and amine (A3-coupling) was developed. A diverse range of propargylamines were obtained in moderate to

Indium-catalyzed highly efficient three-component coupling of aldehyde, alkyne, and amine via C-H bond activation

(Chemical Equation Presented) In this paper, indium(III) chloride was found to be a highly effective catalyst for the three-component coupling reactions of aldehydes, alkynes, and amines (A3-coupling) via C-H activation. The reactions could be

Iron-catalyzed ligand-free three-component coupling reactions of aldehydes, terminal alkynes, and amines

The results on the ligand-free three-component coupling reactions of aldehydes, terminal alkynes, and amines, catalyzed by highly efficient FeCl 3 in the absence of any ligand, were reported. Various iron sources were screened in a model reacti

Zn(OAc)2·2H2O: a versatile catalyst for the one-pot synthesis of propargylamines

An inexpensive and readily available catalyst, Zn(OAc)2·2H2O is successfully evaluated for effective one-pot synthesis of propargylamines with moderate to excellent yields for most of the substrates screened, without the need of base, co-catalyst or additive in the presence of air.