105973-93-1

Basic information

• Product Name: 3-methyl-N₁-phenylbenzene-1,2-diamine
• Synonyms: 3-methyl-N₁-phenylbenzene-1,2-diamine
• CAS NO: 105973-93-1
• Molecular Weight: 198.268
• Mol File: 105973-93-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-methyl-N₁-phenylbenzene-1,2-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methyl-N₁-phenylbenzene-1,2-diamine(105973-93-1)
• EPA Substance Registry System: 3-methyl-N₁-phenylbenzene-1,2-diamine(105973-93-1)

Safety Data

• Hazardous Substances Data: 105973-93-1(Hazardous Substances Data)

Upstream product

• 220495-97-6 3-methyl-2-nitrodiphenylamine 
• 108-86-1 bromobenzene 
• 62-53-3 aniline 
• 52414-97-8 1-bromo-3-methyl-2-nitro-benzene 
• 601-87-6 3-methyl-2-nitroaniline 

Downstream Products

• 667919-12-2 4-methyl-1-phenyl-1H-benzo[d]imidazole 
• 1393175-96-6 (R)-1-(4-methyl-1-phenyl-1H-benzoimidazol-2-yl)ethylamine 
• 1393175-99-9 (S)-1-(4-methyl-1-phenyl-1H-benzoimidazol-2-yl)ethylamine 
• 1393176-01-6 [(S)-1-(2-methyl-6-phenylaminophenylcarbamoyl)ethyl]carbamic acid tert-butyl ester 
• 1393175-98-8 [(R)-1-(2-methyl-6-phenylaminophenylcarbamoyl)ethyl]carbamic acid tert-butyl ester 
• 1393175-97-7 [(R)-1-(4-methyl-1-phenyl-1H-benzoimidazol-2-yl)ethyl]carbamic acid tert-butyl ester 
• 1393176-00-5 [(S)-1-(4-methyl-1-phenyl-1H-benzoimidazol-2-yl)ethyl]carbamic acid tert-butyl ester 
• 1393180-44-3 (S)-N-(1-(4-methyl-1-phenyl-1H-benzo[d]imidazol-2-yl)ethyl)-9H-purin-6-amine 
• 1393180-45-4 (R)-N-(1-(4-methyl-1-phenyl-1H-benzo[d]imidazol-2-yl)ethyl)-9H-purin-6-amine 
• 667919-14-4 1-phenyl-1H-benzoimidazole-4-carboxylic acid 

Relevant articles and documents

Ni-Catalyzed Dual C-H Annulation of Benzimidazoles with Alkynes for Synthesis of π-Extended Heteroarenes

Transition metal catalyzed dual C-H activation and annulation with alkynes was an attractive protocol to construct polycyclic π-extended structures. However, most of them were dominated by noble metal catalysts. Disclosed herein was the study of base-metal Ni-catalysis for dual C-H annulation of N-aromatic imidazole, which produced a range of desired polycyclic aza-quinolines in 48-95% yields. The use of bifunctional phosphine oxide ligand proved to be critical for success.

Structure-activity relationships for 1-phenylbenzimidazoles as selective ATP site inhibitors of the platelet-derived growth factor receptor

1-Phenylbenzimidazoles are shown to be a new class of ATP-site inhibitors of the platelet-derived growth factor receptor (PDGFR). Structure- activity relationships (SARs) are narrow, with closely related heterocycles being inactive. A systematic study of