52414-97-8

Basic information

• Product Name: 3-BROMO-2-NITROTOLUENE
• Synonyms: 3-BROMO-2-NITROTOLUENE 98%;3-bromo-2-nitrobenzene;3-Bromo-2-nitrotoluene,98%;1-BroMo-3-Methyl-2-nitrobenzene;6-Bromo-2-methyl-1-nitrobenzene;3-BROMO-2-NITROTOLUENE;2-Nitro-3-Bromo Toluene
• CAS NO: 52414-97-8
• Molecular Formula: C₇H₆BrNO₂
• Molecular Weight: 216.03
• Product Categories: Aromatic Hydrocarbons (substituted) & Derivatives;Nitro Compounds;Nitrogen Compounds;Organic Building Blocks
• Mol File: 52414-97-8.mol
• Article Data: 4

Chemical Properties

• Melting Point: 25-29 °C(lit.)
• Boiling Point: 267℃
• Flash Point: >230 °F
• Appearance: yellow crystalline low melting mass
• Density: 1.612 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0689mmHg at 25°C
• Refractive Index: 1.6120 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 3-BROMO-2-NITROTOLUENE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-2-NITROTOLUENE(52414-97-8)
• EPA Substance Registry System: 3-BROMO-2-NITROTOLUENE(52414-97-8)

Safety Data

• Hazard Codes: Xn
• Statements: 36/37/38-20/21/22
• Safety Statements: 36/37/39-26-22
• WGK Germany: 3
• Hazardous Substances Data: 52414-97-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H6BrNO2/c1-5-3-2-4-6(8)7(5)9(10)11/h2-4H,1H3

Upstream product

• 591-17-3 meta-bromotoluene 
• 60310-07-8 3-Methyl-2-nitrobenzenecarboxamide 
• 50424-93-6 3-methyl-2-nitrobenzoyl chloride 
• 5437-38-7 3-methyl-2-nitrobenzoic acid 
• 540-80-7 tert.-butylnitrite 
• 601-87-6 3-methyl-2-nitroaniline 
• 108-44-1 1-amino-3-methylbenzene 
• 70343-09-8 2,3-dinitro-4-methylaniline 
• 88-72-2 1-methyl-2-nitrobenzene 
• 1600-27-7 mercury(II) diacetate 

Downstream Products

• 53848-17-2 2-bromo-6-methylaniline 
• 116529-61-4 3-bromo-2-nitrobenzoic acid 
• 95-46-5 2-methylphenyl bromide 
• 60004-40-2 3,2'-Dimethyl-2-nitro-biphenyl 
• 78787-83-4 1,4,8-trimethyl-carbazole 
• 1730-37-6 1-methylfluorene 
• 116436-11-4 N-(2-bromo-6-methylphenyl)acetamide 
• 861791-77-7 2-acetylamino-3-bromo-benzoic acid 
• 857544-42-4 [3-(3-carboxy-2-nitro-phenylsulfanyl)-4-methoxy-phenyl]-acetic acid 
• 1072928-81-4 3-methyl-N-1-propyl-benzene-1,2-diamine 
• 94870-32-3 N-[1,1’-biphenyl]-2-yl-N-[(4-methylphenyl)sulfonyl]glycine 
• 1217169-42-0 N-([1,1′-biphenyl]-2-yl)-N-(4-nitrobenzenesulfonyl)glycine 
• 24127-35-3 7-Oxo-5-(p-toluolsulfonyl)-6,7-dihydro-5H-dibenzazepin 
• 1159406-28-6 5-[(4-nitrophenyl)sulfonyl]-5,6-dihydro-7H-dibenzo[b,d]azepin-7-one 

Relevant articles and documents

Decarboxylative Halogenation and Cyanation of Electron-Deficient Aryl Carboxylic Acids via Cu Mediator as Well as Electron-Rich Ones through Pd Catalyst under Aerobic Conditions

Simple strategies for decarboxylative functionalizations of electron-deficient benzoic acids via using Cu(I) as promoter and electron-rich ones by employing Pd(II) as catalyst under aerobic conditions have been established, which lead to smooth synthesis of aryl halides (-I, Br, and Cl) through the decarboxylative functionalization of benzoic acids with readily available halogen sources CuX (X = I, Br, Cl), and easy preparation of benzonitriles from decarboxylative cyanation of aryl carboxylic acids with nontoxic and low-cost K4Fe(CN)6 under an oxygen atmosphere for the first time.

Indazole derivatives as CRF antagonists

This invention relates to compounds which are generally CRF-1 receptor antagonists and which are represented by Formula I or Formula II: wherein R3 is optionally substituted aryl or heteroaryl, R1 and R2 are as defined in