106-78-5

Usage

Uses

Used in Adhesives, Coatings, and Sealants Industry:
BIS[2-(2-CHLOROACETOXY)ETHYL] ETHER is used as a solvent and plasticizer for enhancing the flexibility, workability, and performance of adhesives, coatings, and sealants. Its properties allow for improved product quality and durability.
Used in Cosmetics and Personal Care Products Industry:
In the cosmetics and personal care sector, BIS[2-(2-CHLOROACETOXY)ETHYL] ETHER serves as an ingredient that helps in the formulation of various products. It contributes to the texture, consistency, and stability of these products, ensuring their effectiveness and longevity.
It is crucial to handle BIS[2-(2-CHLOROACETOXY)ETHYL] ETHER with care due to its potential harmful effects if not properly managed and controlled. This underscores the importance of adhering to safety protocols during its use in different applications.

Upstream product

• 79-04-9 chloroacetyl chloride 
• 111-46-6 diethylene glycol 
• 104-15-4 toluene-4-sulfonic acid 
• 79-11-8 chloroacetic acid 

Downstream Products

• 1127406-70-5 C₂₂H₂₄N₂O₉ 
• 1135131-48-4 C₂₂H₂₀N₂O₁₃ 

Relevant academic research and scientific papers

Rational design, synthesis and evaluation of new azido-ester structures as green energetic plasticizers

Computer-aided molecular design (CAMD) is a well-known tool for the theoretical assessment of chemical structures before their experimental synthesis. In this study, we used this method to consider the important criteria for a chemical structure as an energetic plasticizer for an energetic azido binder. The number of new azido-ester structures were initially designed, and their physicochemical and energetic properties were determinedviatheoretical calculation by molecular dynamics simulations and machine learning-based methods. Considering the balances between several criteria, two of these theoretical chemical structures (including GTAA (glyceryl tris(azidoacetate)) and TEGBAA (triethyleneglycol bis(azidoacetate))) were then selected, synthesized, and characterized. The comparison of experimental and theoretical results to evaluate the physicochemical properties of these new azido-ester plasticizers showed an acceptable agreement between the two methods. Finally, the compatibility and efficiency of these two new azido-ester plasticizers on the rheological and thermal properties of glycidyl azide polymer (GAP) were investigated using rheometry and DSC analyses, and compared with some common energetic plasticizers. The results confirmed that these two new azido-esters are appropriate plasticizers for GAP since they exhibited higher safety over comparable plasticizers, in addition to the real performance.

A novel fluorescence sensor for K+ based on bis-Bodipy: The ACQ effect controlled by cation complexation of pseudo crown ether ring

Three novel bis-Bodipy 3a–3c bridged with crown ether chain were prepared in yields of 70–78%. Their complexation absorption and fluorescent spectra for fourteen metal ions suggested that compound 3b exhibited the selective response for K+ with

Antibacterial activities of five cationic gemini surfactants with ethylene glycol bisacetyl spacers

A series of cationic gemini surfactants containing two dimethylalkylammonium chains linked by ethylene glycol bisacetyl spacers were synthesized [G m-AnA-m, G = gemini surfactant, m = 12 (-C12H25), 14 (-C14H29), or 16 (-C16H33), A = acetyl, and n = 2, 3, or 4 is the number of ethylene glycol units in the spacers]. Because of the inductive effect of the oxygen atom in the spacer, acylation can take place using chloroacetyl chloride instead of bromoacetyl bromide which helps to limit the use of environmentally harmful reagents. Critical micelle concentrations were determined using conductivity measurements. The antibacterial activities of the surfactants against Gram-positive bacterium Staphylococcus aureus and Gram-negative bacterium Escherichia coli were evaluated from the minimum inhibitory concentration (MIC), minimum bacterial concentration, a time-kill study, and the inhibitory zone. Increasing the length of the spacer did not result in an obvious change of antibacterial activity. However, increasing the length of the alkyl chain apparently increased the antibacterial activity against S. aureus but decreased the antibacterial activity against E. coli. The G12-A2A-12 surfactant had the lowest CMC of 1.26 mmol L-1 and exhibited the best antibacterial activity with a MIC of 32 μg mL-1 toward S. aureus and 64 μg mL-1 toward E. coli in the presence of 105 CFU of bacteria. This work indicated that these cationic gemini surfactants have potential applications as antibacterial agents and emulsifiers.

Synthesis, Characterization and Solution Properties of Novel Cationic Ester-Based Gemini Surfactants

The present investigation involves the synthesis of a series of novel green ethylene oxide-linked diester-functionalized cationic gemini surfactants 2,2′-[(oxybis(ethane-1,2-diyl))bis(oxy)]bis(N-alkyl-N,N-dimethyl-2-oxoethanaminium) dichloride (Cm-DEG-Cm; m = 12, 14, 16). These compounds were characterized by 1H-NMR, MS-ESI (+), FT-IR spectroscopy and elemental analysis; their solution properties were evaluated by surface tension and rheology measurements. The dimeric surfactant, Cm-DEG-Cm, possesses improved physicochemical properties as compared to its monomeric counterpart. Much lower critical micelle concentration (cmc) makes the cationic gemini surfactants more useful for the biomedical, pharmaceutical, industrial and academic sectors. Longer the alkyl chain of surfactants lower are the cmc values, the order is C16-DEG-C16 14-DEG-C14 12-DEG-C12. For all the three synthesized gemini surfactants no cloud point was noticed in between the temperatures 0 °C to 100 °C at the concentrations 0.002 mM, 0.02 mM and 0.2 mM of the aqueous surfactant solutions which is a beneficial factor for the use of these amphiphiles in various areas of application.

(meth)acrylate compound

The invention relates to a (meth)acrylate compound as well as a preparation method and application thereof. The compound has the following structure shown in the specification, and the preparation method is simple. The compound has the advantages of low odor or no odor, low irritation or no irritation, low viscosity, high reactivity and moderate glass transition temperature of the obtained polymer, can participate in free radical polymerization, has favorable flexibility and adhesivity, and can be used in light-cured ink, paint and adhesives.

Bis-biphenylacrylonitrile bridged with crown ether chain: A novel fluorescence sensor for Fe3+in aqueous media

The design and synthesis of novel fluorescence sensors for Fe3+ in aqueous media have important prospects for practical applications. In this work, the novel bis-biphenylacrylonitrile bridged with crown ether chains 3a-3c were prepared in yields of 73-80%. Compounds 3a-3c exhibited high fluorescence in aqueous media based on the AIE effect. The sensing abilities for a series of metal ions suggested that the compound 3b possessed the selective detection for Fe3+ in aqueous media with strong fluorescence quenching. The detection limit of compound 3b for Fe3+ was 1.67 × 10-7 M and the sensing mechanism was proposed with the assistance of 1H NMR and MS studies. Compound 3b displayed excellent fluorescence imaging properties with a sensing ability for Fe3+ in living cell systems, indicating the good application prospect for sensing Fe3+ in aqueous media and complex environments. This journal is

Bio-physicochemical analysis of ethylene oxide-linked diester-functionalized green cationic gemini surfactants

A novel series of oxy-diester-functionalized gemini surfactants (Cm-E2O-Cm) was synthesized and the physicochemical parameters were evaluated by surface tension and steady-state fluorescence measurements. Negative values of Gibbs free energy change of adsorption and micellization indicate that adsorption and micellization of Cm-E2O-Cm gemini surfactants are spontaneous. These surfactants have lower Krafft points and thus better solubility. Besides, they exhibit excellent foam and micro-emulsion stability. Interestingly, these geminis show low cytotoxicity, as revealed by HC50 analysis. FT-IR spectra after alkaline treatment confirm their cleavable nature. Moreover, a fascinating feature of these geminis is their considerably high biodegradability. Thus, a comprehensive study of the synthesized gemini surfactants has been carried out that may be significant for potential applications in various fields, more specifically in biomedicine and cosmetics, where efficiency and safety are strictly connected.

Absorbable polyurethanes and methods of use thereof

Disclosed are novel bioabsorbable and biodegradable monomer compounds, bioabsorbable and biodegradable polymers therefrom, and methods of making such monomers and polymers, which are useful in pharmaceutical delivery systems, tissue engineering applicatio

HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS

The present invention relates to the discovery of new class of linear and multiarmed hydrolysable linkers and cross linkers for use in the synthesis of biodegradable polymers such as, polyesters, polyurethanes, polyamides, polyureas and degradable epoxy amine resin. The linear and multiarmed hydrolysable linkers of the present invention include symmetrical and/or unsymmetrical ether carboxylic acids, amines, amide diols, amine polyols and isocyanates.

BIOABSORBABLE POLYMERS FROM BIOABSORBABLE POLYISOCYANATES AND USES THEREOF

Novel bioabsorbable and/or biocompatible polyurethanes, polyureas, polyamideurethanes and polyureaurethanes with tunable physical, mechanical properties and hydrolytic degradation profiles are provided for use in biomedical applications such as stents, stent coatings, scaffolds, foams, and films. The disclosed polymers may be derived from biocompatible and/or bioabsorbable polyisocyanates. The present invention also relates to new and improved methods for the preparation of the biocompatible and/or bioabsorbable polyisocyanates.