106047-28-3

Basic information

• Product Name: 6-broMo-2,3'-bipyridine
• Synonyms: 6-broMo-2,3'-bipyridine;2-bromo-6-(pyridin-3-yl)pyridine
• CAS NO: 106047-28-3
• Molecular Formula: C₁₀H₇BrN₂
• Molecular Weight: 235.07998
• Mol File: 106047-28-3.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 6-broMo-2,3'-bipyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-broMo-2,3'-bipyridine(106047-28-3)
• EPA Substance Registry System: 6-broMo-2,3'-bipyridine(106047-28-3)

Safety Data

• Hazardous Substances Data: 106047-28-3(Hazardous Substances Data)

Usage

General Description

6-bromo-2,3'-bipyridine is a chemical compound with the molecular formula C10H7BrN2. It is a derivative of bipyridine and contains a bromine atom at the 6-position of the aromatic ring. 6-broMo-2,3'-bipyridine is commonly used as a building block in organic synthesis and coordination chemistry. It has been investigated for its potential applications in materials science, catalysis, and pharmaceutical research. Additionally, 6-bromo-2,3'-bipyridine has been studied as a ligand for the preparation of coordination complexes and as a precursor for the synthesis of various functionalized bipyridine derivatives. Overall, this chemical has diverse potential uses in various fields of scientific research and industrial applications.

Upstream product

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Relevant articles and documents

Synthesis of Bis-heteroaryls Using Grignard Reagents and Pyridylsulfonium Salts

Herein are reported ligand-coupling reactions of Grignard reagents with pyridylsulfonium salts. The method has wide functional group tolerance and enables the formation of bis-heterocycle linkages, including 2,4′-, 2,3′-, and 2,2′-bipyridines, as well as pyridines linked to pyrimidines, pyrazines, isoxazoles, and benzothiophenes. The methodology was successfully applied to the synthesis of the natural products caerulomycin A and E.

2-Pyridyl and 3-pyridylzinc bromides: direct preparation and coupling reaction

A facile synthetic approach to the direct preparation of 2-pyridyl and 3-pyridylzinc bromides has been demonstrated using Rieke zinc with 2-bromopyridine and 3-bromopyridine, respectively. A variety of different electrophiles have been coupled with the resulting organozinc reagents to give the corresponding cross-coupling products in moderate to good yields.

A facile synthetic approach to the preparation of 3-pyridyl derivatives: Preparations and coupling reactions of 3-pyridylzinc and its analogues

A facile synthetic approach to the direct preparation of 3pyridylzinc bromide has been demonstrated using Rieke zinc with 3-bromopyridine in the presence of a catalytic amount of lithium chloride. A variety of different electrophiles have been coupled to give the corresponding cross-coupling products in moderate to good yields. Also, this methodology has been expanded to the preparation of the corresponding organozinc reagents of 3-bromopyridine analogues. Georg Thieme Verlag Stuttgart.