10605-66-0

Basic information

• Product Name: 4-methylpent-2-yne-1,4-diol
• Synonyms: 4-methylpent-2-yne-1,4-diol;4-Methyl-2-pentyne-1,4-diol;2-Pentyne-1,4-diol, 4-methyl-;Ai3-28490;Einecs 234-235-7
• CAS NO: 10605-66-0
• Molecular Formula: C₆H₁₀O₂
• Molecular Weight: 114.1424
• EINECS: 234-235-7
• Mol File: 10605-66-0.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 205.2°Cat760mmHg
• Flash Point: 92.8°C
• Appearance: /
• Density: 1.077g/cm³
• Vapor Pressure: 0.0603mmHg at 25°C
• Refractive Index: 1.494
• PKA: 13.07±0.10(Predicted)
• CAS DataBase Reference: 4-methylpent-2-yne-1,4-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methylpent-2-yne-1,4-diol(10605-66-0)
• EPA Substance Registry System: 4-methylpent-2-yne-1,4-diol(10605-66-0)

Safety Data

• Hazardous Substances Data: 10605-66-0(Hazardous Substances Data)

Usage

General Description

4-methylpent-2-yne-1,4-diol is a chemical compound with the molecular formula C6H10O2. It is a diol, which means it has two hydroxyl (OH) functional groups. 4-methylpent-2-yne-1,4-diol is a colorless liquid and is commonly used as a chemical intermediate in the synthesis of other organic compounds. It is also used in the production of pharmaceuticals, coatings, and adhesives. This chemical is known for its high reactivity and is commonly handled and stored under inert gas atmospheres to prevent oxidation. 4-methylpent-2-yne-1,4-diol is also used as a starting material in the preparation of various polymers and has potential applications in the fields of materials science and engineering.

InChI:InChI=1/C6H10O2/c1-6(2,8)4-3-5-7/h7-8H,5H2,1-2H3

Upstream product

• 107-19-7 propargyl alcohol 
• 67-64-1 acetone 
• 925-90-6 ethylmagnesium bromide 
• 115-19-5 2-methyl-but-3-yn-2-ol 
• 50-00-0 formaldehyd 
• 259880-64-3 5-{[tert-butyl(dimethyl)silyl]oxy}-2-methylpent-3-yn-2-ol 
• 13030-38-1 5-(1-butoxy-ethoxy)-2-methyl-pent-3-yn-2-ol 
• 14092-32-1 2-methyl-5-<(tetrahydro-2H-pyran-2-yl)-oxy>-3-pentyn-2-ol 

Downstream Products

• 1601497-20-4 4-methyl-2-phenylpenta-2,3-dien-1-ol 
• 1003-17-4 2,2-dimethyltetrahydrofuran 
• 902451-94-9 (2S,3S)-Toluene-4-sulfonic acid 2-methyl-3-[3-methyl-3-(tetrahydropyran-2-yloxy)butyl]oxiranylmethyl ester 
• 3123-97-5 dihydro-5,5-dimethyl-2(3H)-furanone 
• 167100-91-6 2-methyl-5-tosyloxy-3-pentyn-2-ol 
• 10605-68-2 4-methyl-4-penten-2-yn-1-ol 
• 3132-22-7 5,5-dimethyldihydrofuran-3(2H)-one 
• 1422127-87-4 C₂₄H₂₅F₆N₃O₂S 

Relevant articles and documents

Synthesis of 8-methylnonane-1,6,7-trien-4-one and related allenes as potentially useful synthetic precursors

The allenic ketone 8-methylnonane-1,6,7-trien-4-one and related allenes have been synthesized from simple commercially available materials. Since allenes analogous to 8-methylnonane-1,6,7-trien-4-one have previously been transformed to substituted bicyclo[3.3.0]octanones via corresponding bicyclo[3.2.0]heptanones, it is anticipated that the present allenic ketone may also undergo similar transformations. Substituted bicyclo[3.3.0]octanones are known synthetic precursors of tricyclic sesquiterpenes. Thus, 8-methylnonane-1,6,7- trien-4-one presents itself as a possible precursor for the synthesis of tricyclopentanoid ring system present in sesquiterpenes such as hirsutene and Δ9(12)-capnellene.

A synthesis of japanese hop ether

Reaction of 2,5-dihydro-2,2-dimethylfuran with ethynehexacarbonyldicobalt lacks significant regioselectivity, but nevertheless makes possible the synthesis of (±)-hop ether (cis-hexahydro-1,1-dimethyl-4-methylene-1H-cyclopenta[c]furan) in five steps from cis-4-methylpent-2-ene-1,4-diol.

A novel RET inhibitor. Pharmaceutical composition and use thereof

The invention belongs to the field of medicines, and relates to a novel RET inhibitor, a pharmaceutical composition and application thereof. In particular, the invention relates to a compound represented by formula (I), a stereoisomer, a tautomer, an oxynitride, a solvate, a metabolite, a pharmaceutically acceptable salt or prodrug thereof, I said compound and a pharmaceutical composition thereof for the manufacture of a medicament, in particular for the treatment and prophylaxis and RET of diseases and disorders associated with irritable bowel syndrome.

Novel Crosslinking Agent Compound and Superabsorbent Polymer Prepared by Using the Same

Provided are a novel crosslinking agent compound, and a superabsorbent polymer prepared by using the same. More particularly, provided are a crosslinking agent compound having a novel structure, which exhibits excellent crosslinking property and thermal degradability, and a superabsorbent polymer prepared by using the same.