106053-23-0

Upstream product

• 3423-13-0 1-benzyl-6,7-dimethoxy-N-methyl-1,2,3,4-tetrahydroisoquinoline 
• 541-41-3 chloroformic acid ethyl ester 
• 100-42-5 styrene 
• 343780-59-6 N-[2-(2-iodo-4,5-dimethoxyphenyl)ethyl]carbamic acid ethyl ester 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 17889-63-3 N-<2-(3,4-Dimethoxyphenyl)ethyl>carbamidsaeureethylester 
• 343780-62-1 N-[2-(4,5-dimethoxy-2-styrylphenyl)ethyl]carbamic acid ethyl ester 
• 74-88-4 methyl iodide 
• 99272-79-4 2-(N-carbethoxy-N-methyl-2-aminoethyl)-4,5-dimethoxybenzaldehyde 
• 100-52-7 benzaldehyde 

Downstream Products

• 343780-60-9 7,8-dimethoxy-2-methyl-5-styryl-3,4-dihydro-2H-isoquinolin-1-one 

Relevant academic research and scientific papers

First total syntheses of the 1,2,3,4-tetrahydronaphtho[2,1-f]isoquinolines annoretine and litebamine

We describe here the first total synthesis of the two natural 1,2,3,4-tetrahydronaphtho[2,1-f]isoquinolines, annoretine and litebamine, from [2-(2-styrylphenyl)ethyl]methylcarbamic acid ethyl esters. The key steps were the Bischler-Napieralski cyclization

First total synthesis of the 1,2,3,4-tetrahydronaphtho[2,1-f]isoquinoline annoretine

Here we describe the first total synthesis of the 1,2,3,4-tetrahydronaphtho[2,1-f]isoquinoline (6) annoretine from N-carbethoxy-o-styrylphenylethylamines 2. The key steps were the Bischler-Napieralski reaction to form the isoquinoline unit and photocycliz

Syntheses og Stilbenes with a C2-Sidechain in o-Position and of their Deuteriated Analogues

Syntheses of o-(β-aminoethyl)-stilbene-urethanes (types 1, 2 and 3) and o-(β-phenethyl)-stilbenes 4 are described.The urethanes are obtained by degradation of 1-benzyl-1,2,3,4-tetrahydroisoquinolines with ethylchloroformate; 4 is synthesized by reduction of desoxybenzoines, followed by o-formylation and Wittig-reaction.The deuteriated isotopomers were obtained via the corresponding deuteriated precursors. - Keywords: Stilbenes, o-substituted; Deuteriated compounds

Reductive Dicarbonyl Coupling with Low-valent Titanium Reagents: a New Entry to Phenanthrene Alkaloids

A new and direct synthesis of phenanthrene alkaloids using a low-valent titanium reagent is described which is compatible with ethoxycarbonyl as the N-protecting group.