106144-99-4

Upstream product

• 96-08-2 R-(+)-limonene diepoxide 
• 106144-98-3 (1S,2S,4R)-4-(1'-hydroxy-1',5'-dimethyl-4'-hexenyl)-1-methyl-2-phenylselenocyclohexanol 
• 106144-97-2 (1'R)-6-methyl-2-(3',4'-epoxy-4'-methylcyclohexyl)-5-hepten-2-ol 
• 106144-98-3 (1R,2R,4S)-4-(1'-hydroxy-1',5'-dimethyl-4'-hexenyl)-1-methyl-2-phenylselenocyclohexanol 
• 5989-54-8 (-)-(S)-limonene 
• 106144-97-2 (1'S)-6-methyl-2-(3',4'-epoxy-4'-methylcyclohexyl)-5-hepten-2-ol 
• 96-08-2 (4S)-(-)-1,2,8,9-diepoxy-p-menthane 
• 96-08-2 (4R)-(+)-1,2,8,9-diepoxy-p-menthane 
• 5989-27-5 D-limonene 
• 106144-98-3 (R)-4-(1-Hydroxy-1,5-dimethyl-hex-4-enyl)-1-methyl-2-phenylselanyl-cyclohexanol 

Downstream Products

• 110715-84-9 (-)-hernandulcin 
• 110715-85-0 (6R,1'S)-epi-hernandulcin 
• 106145-00-0 (6S,1'R)-6-(1'-hydroxy-1',5'-dimethyl-4'-hexenyl)-3-methyl-2-cyclohexenone 
• 95602-94-1 (6S,1'S)-6-(1'-hydroxy-1',5'-dimethyl-4'-hexenyl)-3-methyl-2-cyclohexenone 

Relevant academic research and scientific papers

SYNTHESIS OF (6S,1'S)-(+)-HERNANDULCIN, A SWEETNER, AND ITS STEREOISOMERS

All of the four possible stereoisomers of hernandulcin were synthesized starting from the enantiomers of limonene.The absolute configuration of the naturally occuring and sweet-tasting (+)-hernandulcin was established as 6S,1'S.Other stereoisomers were not sweet at all.

SYNTHESIS AND ABSOLUTE CONFIGURATION OF (+)-HERNANDULCIN. A NEW SESQUITERPENE WITH INTENSELY SWEET TASTE

The absolute configuration of (+)-hernandulcin was shown to be 6S,1'S by synthesizing it from (R)-(+)-limonene.