1062071-57-1

Basic information

• Product Name: C₂₂H₂₈Cl₂N₄O₄S
• CAS NO: 1062071-57-1
• Molecular Weight: 515.461
• Mol File: 1062071-57-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₂H₂₈Cl₂N₄O₄S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₂₈Cl₂N₄O₄S(1062071-57-1)
• EPA Substance Registry System: C₂₂H₂₈Cl₂N₄O₄S(1062071-57-1)

Safety Data

• Hazardous Substances Data: 1062071-57-1(Hazardous Substances Data)

Upstream product

• 63352-99-8 (3,5-dichlorophenyl)hydrazine hydrochloride 
• 96-41-3 Cyclopentanol 
• 1295576-00-9 C₂₄H₃₀Cl₂N₄O₄ 
• 1295575-82-4 C₁₉H₂₁Cl₃N₄O₃ 
• 10147-37-2 Isopropylsulfonyl chloride 
• 86483-43-4 4,5-dichloro-2-(3,5-dichlorophenyl)pyridazin-3-one 

Relevant articles and documents

The synthesis and structure-activity relationship of pyridazinones as glucan synthase inhibitors

A structure-activity relationship study of the lead 5-[4-(benzylsulfonyl) piperazin-1-yl]-4-morpholino-2-phenyl-pyridazin-3(2H)-one 1 has resulted in the identification of 2-(3,5-difluorophenyl)-4-(3-fluorocyclopentyloxy)-5-[4- (isopropylsulfonyl)piperazin-1-yl]-pyridazin-3(2H)-one 11c as a β-1,3-glucan synthase inhibitor. Compound 11c exhibited significant efficacy in an in vivo mouse model of Candida glabrata infection.