106256-79-5

Upstream product

• 100-39-0 benzyl bromide 
• 106294-96-6 8-azido-3,6-dioxaoctyl 2-acetamido-4,6-O-benzylidene-2-deoxy-β-D-glucopyranoside 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 86520-52-7 2-[2-(2-azidoethoxy)ethoxy]ethanol 
• 77544-68-4 8-tosyloxy-3,6-dioxaoctanol 
• 86520-54-9 8-azido-3,6-dioxaoctyl 2-acetamido-2-deoxy-β-D-glucopyranoside 
• 86520-53-8 2-[2-(2-Azidoethoxy)ethoxy]ethyl 3,4,6-tri-O-acetyl-2-N-acetamido-2-deoxy-β-D-glucopyranoside 
• 3068-34-6 Acetic acid (2R,3S,4R,5R,6R)-3-acetoxy-2-acetoxymethyl-5-acetylamino-6-chloro-tetrahydro-pyran-4-yl ester 
• 112-27-6 2,2'-[1,2-ethanediylbis(oxy)]bisethanol 

Downstream Products

• 106256-80-8 8-azido-3,6-dioxaoctyl 2-acetamido-3-O-benzyl-2-deoxy-β-D-glucopyranoside 
• 106256-83-1 8-azido-3,6-dioxaoctyl 3-O-benzyl-2-deoxy-6-O-<2,3,6-tri-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-β-D-gglucopyranosyl>-β-D-glucopyrnoside 

Relevant academic research and scientific papers

STREPTOCOCCUS PNEUMONIAE TYPE XIV POLISACCHARIDE: SYNTHESIS OF A REPEATING BRANCHED TETRASACCHARIDE WITH DIOXA-TYPE SPACER-ARMS

β-Glycosides of 2-acetamido-2-deoxy-D-glucopyranose were synthesised, using either 7-methoxycarbonyl-3,6-dioxa-1-heptanol or 8-azido-3,6-dioxa-1-octanol.Selective β-lactosylation of 7-methoxycarbonyl-3,6-dioxaheptyl 2-acetamido-3-O-benzyl-2-deoxy-β-D-glucopyranoside with hepta-O-acetyl-lactosyltrichloroacetimidate, followed by β-galactosylation of the secondary hydroxyl group with O-(2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl)trichloroacetamidate, catalytic hydrogenolysis, and O-deacetylation, gave 7-methoxycarbonyl-3,6-dioxaheptyl 2-acetamido-2-deoxy-4-O-β-D-galactopyranosyl-6-O-(4-O-β-D-galactopyranosyl-β-D-glucopyranosyl)-β-D-glucopyranoside.Selective β-lactosilation of 8-azido-3,6-dioxaoctyl 2-acetamido-3-O-benzyl-2-deoxy-β-D-glucopyranoside with hepta-O-acetyl-lactosyl bromide in the presence of silver triflate, followed by condensation with 2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl bromide in the presence of silver triflate, catalytic hydrogenolysis, and O-deacetylation, gave 8-azido-3,6-dioxaoctyl 2-acetamido-2-deoxy-4-O-β-D-galactopyranosyl-6-O-(4-O-β-D-galactopyranosyl-β-D-glucopyranosyl)-β-D-glucopyranoside.