1062601-62-0

Basic information

• Product Name: (-)-(3R,4S)-1-benzyl-3,4-epoxypiperidine
• Synonyms: (-)-(3R,4S)-1-benzyl-3,4-epoxypiperidine
• CAS NO: 1062601-62-0
• Molecular Weight: 189.257
• Mol File: 1062601-62-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (-)-(3R,4S)-1-benzyl-3,4-epoxypiperidine(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-(3R,4S)-1-benzyl-3,4-epoxypiperidine(1062601-62-0)
• EPA Substance Registry System: (-)-(3R,4S)-1-benzyl-3,4-epoxypiperidine(1062601-62-0)

Safety Data

• Hazardous Substances Data: 1062601-62-0(Hazardous Substances Data)

Upstream product

• 1384732-89-1 C₁₀H₂₀O₈S₂ 
• 1384732-93-7 C₁₅H₂₁NO₂ 
• 40240-12-8 1-benzyl-1,2,3,6-tetrahydropyridine 
• 868051-83-6 (3R,4S)-1-benzyl-piperidine-3,4-diol 
• 86795-44-0 3,4-O-isopropylidene-2-deoxy-D-ribose 
• 84608-35-5 2-((4S,5R)-5-Hydroxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethanol 
• 725715-12-8 3-(phenylmethyl)-7-oxa-3-azabicyclo[4.1.0]heptane 

Relevant articles and documents

Synthetic approaches to a chiral 4-amino-3-hydroxy piperidine with pharmaceutical relevance

Four synthetic strategies were evaluated towards the preparation of (-)-(3R,4R)-1-benzyl-4-(benzylamino)piperidin-3-ol (1), which was constructed with control over the relative and absolute stereochemistry of the 4,3-amino alcohol moiety. The first strategy employed a novel RhI catalyzed asymmetric hydrogenation, while two other strategies exploited the existing stereochemistry in 2-deoxy-d-ribose, and the fourth explored both biocatalytic and classical resolution techniques as a means to impart enantioenrichment to racemic intermediates en route to targeted structure (-)-1. The Royal Society of Chemistry 2012.