106263-50-7 Usage
Uses
Used in Pharmaceutical Research and Development:
4-(2-chlorophenyl)-4-oxobutyric acid is used as a research compound for exploring its potential therapeutic properties. Its unique structure and the presence of a 2-chlorophenyl group may contribute to its potential as a pharmaceutical agent, warranting further study in the development of new drugs.
Used in Drug Synthesis:
In the pharmaceutical industry, 4-(2-chlorophenyl)-4-oxobutyric acid is used as a key intermediate in the synthesis of various drugs. Its chemical properties allow it to be a valuable building block in the creation of new medications, potentially leading to the development of novel therapeutics.
Used in Chemical Research:
4-(2-chlorophenyl)-4-oxobutyric acid is also utilized in chemical research to understand its reactivity, stability, and interactions with other compounds. This knowledge can be crucial in optimizing its use in pharmaceutical applications and exploring its potential in other industries, such as materials science or agriculture.
Check Digit Verification of cas no
The CAS Registry Mumber 106263-50-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,6,2,6 and 3 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 106263-50:
(8*1)+(7*0)+(6*6)+(5*2)+(4*6)+(3*3)+(2*5)+(1*0)=97
97 % 10 = 7
So 106263-50-7 is a valid CAS Registry Number.
InChI:InChI=1/C10H9ClO3/c11-8-4-2-1-3-7(8)9(12)5-6-10(13)14/h1-4H,5-6H2,(H,13,14)
106263-50-7Relevant academic research and scientific papers
Asymmetric hydrogenation reaction γ - or δ - ketonato compound (by machine translation)
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Paragraph 0054-0059, (2020/03/06)
The invention relates to the field, of organic chemistry, specifically γ - or δ - keto acid compound asymmetric hydrogenation reaction, reaction formula as follows : Wherein R is H,C. 1 - C6 An alkyl or halogen, is R 1 - 5 in number of substituents . wherein n is 1 or 2;Cat. is a chiral spiro pyrimidyl phosphine ligand iridium complex . and γ - or δ - keto acid compound is subjected to an internal esterification reaction to further prepare a lactone compound. (by machine translation)
Iridium-Catalyzed Asymmetric Hydrogenation of ?- A nd ?-Ketoacids for Enantioselective Synthesis of ?- A nd ?-Lactones
Hua, Yun-Yu,Bin, Huai-Yu,Wei, Tao,Cheng, Hou-An,Lin, Zu-Peng,Fu, Xing-Feng,Li, Yuan-Qiang,Xie, Jian-Hua,Yan, Pu-Cha,Zhou, Qi-Lin
supporting information, p. 818 - 822 (2020/02/15)
A highly efficient asymmetric hydrogenation of ?- A nd ?-ketoacids was developed by using a chiral spiro iridium catalyst (S)-1a, affording the optically active ?- A nd ?-hydroxy acids/lactones in high yields with excellent enantioselectivities (up to >99% ee) and turnover numbers (TON up to 100000). This protocol provides an efficient and practical method for enantioselective synthesis of Ezetimibe.
