106328-99-8Relevant articles and documents
ISOXAZOLIDINE DERIVATIVES
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Page/Page column 20, (2012/09/25)
Anti-inflammatory and antiallergic compounds of the glucocorticosteroid series according to formula (I) defined herein are useful for treating diseases of the respiratory tract characterized by airway obstruction.
Traceless solid-phase synthesis of hydroxylated cyclopentenones
Stathakis, Christos I.,Gallos, John K.
scheme or table, p. 6804 - 6806 (2009/04/07)
Intramolecular nitrone-alkene cycloadditions on solid phase can be performed using polymer-bound hydroxylamine. Condensation of this reagent with sugar derived 4-pentenals followed by N-O cleavage, quaternization of the amine thus produced, and finally oxidative elimination of the amino group detaches the chiral hydroxylated cyclopentenones from the polymer. The natural antibiotic pentenomycin I was prepared in this way.
Structure-activity analysis of a class of orally active hydroxamic acid inhibitors of leukotriene biosynthesis
Summers,Gunn,Martin,Martin,Mazdiyasni,Stewart,Young,Bouska,Dyer,Brooks,Carter
, p. 1960 - 1964 (2007/10/02)
The nature of the carbonyl and nitrogen substituents of hydroxamic acids has a major influence on the biological profile of these compounds. Hydroxamates with small groups such as methyl appended to the carbonyl and relatively large nitrogen substituents