1092971-16-8Relevant articles and documents
Traceless solid-phase synthesis of hydroxylated cyclopentenones
Stathakis, Christos I.,Gallos, John K.
scheme or table, p. 6804 - 6806 (2009/04/07)
Intramolecular nitrone-alkene cycloadditions on solid phase can be performed using polymer-bound hydroxylamine. Condensation of this reagent with sugar derived 4-pentenals followed by N-O cleavage, quaternization of the amine thus produced, and finally oxidative elimination of the amino group detaches the chiral hydroxylated cyclopentenones from the polymer. The natural antibiotic pentenomycin I was prepared in this way.