106334-47-8Relevant articles and documents
β-LACTAM SYNTHESIS: CYCLIZATION VERSUS 1,2-ACYL MIGRATION-CYCLIZATION. THE MECHANISM OF THE 1,2-ACYL MIGRATION-CYCLIZATION
Godfrey, Jollie D.,Mueller, Richard H.,Langen, Derek J. Von
, p. 2793 - 2796 (2007/10/02)
The cyclization of hydroxamate 1 unexpectedly afforded two isomeric β-lactams 2 and 3.The mechanism for the formation of 3 has been shown by carbon-13 labeling to involve a novel 1,2-acyl migration-cyclization process.