106426-96-4Relevant academic research and scientific papers
Practical, asymmetric synthesis of 16-hydroxyeicosa-5(Z),8(Z),11(Z),14(Z)-tetraenoic acid (16-HETE), an endogenous inhibitor of neutrophil activity
Reddy, Y. Krishna,Reddy, L. Manmohan,Capdevila, Jorge H.,Falck
, p. 3719 - 3720 (2007/10/03)
An asymmetric synthesis of 16-HETE, an endogenous inhibitor of neutrophil activity, was achieved in six steps from R-(-)-glycidyl benzyl ether in 28% overall yield.
Highly Enantioselective Rearrangement of (S)-E-α-p-Tolylsulphinyl-α,β-enolates to (R)-E-γ-Hydroxy-α,β-enoates
Kosugi, Hiroshi,Kitaoka, Masaki,Takahashi, Akira,Uda, Hisashi
, p. 1268 - 1270 (2007/10/02)
On treatment with pyridine-camphorsulphonic acid, (S)-E-α-p-tolylsulphinyl-α,β-enoates (4) undergo enantioselectively a sequential prototropic shift and allylic sulphoxide-sulphenate rearrangement to produce (R)-E-γ-hydroxy-α,β-enoates (2) in 64-72percent
