106427-72-9

Basic information

• Product Name: (4Z)-6-<(2RS,4RS,5SR)-2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl>hex-4-enoic acid
• CAS NO: 106427-72-9
• Molecular Weight: 402.875
• Mol File: 106427-72-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (4Z)-6-<(2RS,4RS,5SR)-2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl>hex-4-enoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (4Z)-6-<(2RS,4RS,5SR)-2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl>hex-4-enoic acid(106427-72-9)
• EPA Substance Registry System: (4Z)-6-<(2RS,4RS,5SR)-2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl>hex-4-enoic acid(106427-72-9)

Safety Data

• Hazardous Substances Data: 106427-72-9(Hazardous Substances Data)

Upstream product

• 135-02-4 ortho-anisaldehyde 
• 89-98-5 2-chloro-benzaldehyde 
• 99226-02-5 trans-racemic 2-methoxy-paraconic acid 
• 117621-06-4 2-(2-methoxyphenyl)-5-oxotetrahydrofuran-3-carboxylic acid 
• 106428-02-8 4(Z)-6-(4-o-hydroxyphenyl-2,2-dimethyl-1,3-dioxan-cis-5-yl) hexenoic acid 
• 587-04-2 m-Chlorobenzaldehyde 
• 106428-11-9 4(Z)-erythro-8-hydroxy-7-hydroxymethyl-8-o-hydroxyphenyl-4-octenoic acid 
• 106427-98-9 4(Z)-6-(2-chlorophenyl-4-o-methoxyphenyl-1,3-dioxan-cis-5-yl) hexenoic acid 
• 106306-00-7 4(Z)-erythro-8-hydroxy-7-hydroxymethyl-8-o-methoxyphenyl-4-octenoic acid 
• 106305-99-1 (Z)-6-[(4R,5S)-4-(2-Methoxy-phenyl)-2,2-dimethyl-[1,3]dioxan-5-yl]-hex-4-enoic acid 

Downstream Products

• 1041850-31-0 4(Z)-6-[(2,4,5 cis)-2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]hexenoic acid 

Relevant articles and documents

PPAR Modulators

1,3-dioxane derivatives are described and their use in the treatment of a disease or condition dependent on PPAR modulation, such as diabetes, cancer, inflammation, neurodegenerative disorders and infections.

Improved synthetic routes to the novel thromboxane receptor antagonist ICI 192605: Activity of synthetic 1.3-dioxane intermediates

A study of the synthetic routes to the thromboxane receptor antagonist ICI 192605 4(Z)-6-(2-o-chlorophenyl-4- o-hydroxyphenyl- 1,3-dioxan-cis-5-yl) hexenoic acid is described which led to an improvement in overall synthetic yield from 20 to 55%. In-vitro