106540-34-5

Upstream product

• 106540-31-2 (+)-(S)-3-(tert-butyldimethylsiloxy)-2,2-dimethylcyclohexanone 
• 87655-21-8 (S)-3-hydroxy-2,2-dimethylcyclohexanone 
• 106540-32-3 (3S)-3-t-butyldimethylsilyloxy-2,2,6-trimethylcyclohexanone 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 106540-35-6 (S)-4-t-butyldimethylsilyloxy-2-vinyl-1,3,3-trimethylcyclohexene 
• 106622-48-4 dimethyl (1R,4aS,8aS)-1,4,4a,5,6,7,8,8a-octahydro-5,5,8a-trimethylnaphthalene-1,2-dicarboxylate 
• 6752-77-8 (+)-polygodial 
• 6754-20-7 Polygodial 
• 106540-40-3 (S)-3-ethenyl-2,2,4-trimethyl-3-cyclohexenol 

Relevant academic research and scientific papers

SYNTHESIS OF BOTH THE ENANTIOMERS OF POLYGODIAL, AN INSECT ANTIFEEDANT SESQUITERPENE

Both the natural and unnatural enantiomers of polygodial, an insect antifeedant sesquiterpene of the drimane family, were synthesized starting from (S)-3-hydroxy-2,2-dimethylcyclohexanone as a single chiral source.