106549-35-3Relevant academic research and scientific papers
Synthesis of 2,3-disubstituted-6-chromones of potential medicinal interest
Singh, O. V.,Sangeeta,Khanna, M. S.,Garg, C. P.,Kapoor, R. P.,et al.
, p. 1241 - 1248 (2007/10/02)
The title compounds (12-19) have been synthesized by the condensation of 2,3-disubstituted-6-chromones (8-11) with hydrazine hydrate in the presence of formic or acetic acid.Their structures have been elucidated on the basis o
2,4-Bis(substituted cinnamoyl/pyrazol-3-yl)phenoxyacetic Acid Esters and Hydrazides as Potential Antimicrobial Agents
Sangwan, Naresh K.,Verma, Braham S.,Dhindsa, Kuldip Singh
, p. 672 - 674 (2007/10/02)
Condensation of 2,4-diacetylphenol (I) with substituted benzaldehydes give 2,4-bis(substituted cinnamoyl)phenols (IIIa-c) which on treatment with hydrazine hydrate in acetic or formic acid furnish the corresponding 2,4-bis(1-acetyl/formyl-4,5-dihydro-5-arylpyrazol-3-yl)phenols (Va-f).Alkylation of I, IIIa-c and Va-c with ethyl chloroacetate gives the corresponding ethyl substituted phenoxyacetates (II, IVa-c and VIa-c).Treatment of VIa-c with hydrazine hydrate in ethanol affords the corresponding hydrazides VIIa-c.None of the compounds tested shows any in vitro growth inhibitory activity against Alternaria alternata, Macrophomina phaseolina, Helminthosporium oryzae and Fusarium oxysporum upto a concentration of 100 μg/ml.
