30186-16-4Relevant articles and documents
Kinetics and mechanism of certain acetylation reactions with acetamide/oxychloride in acetonitrile under Vilsmeier-Haack conditions
Venkateswarlu, Marri,Satish Kumar, Mukka,Ramgopal, Soma,Rajanna, Kamatala Chinna,Umesh Kumar, Utkoor,Uppalaiah, Kusampally,Saiprakash, Pondichery Kuppuswamy
, p. 2168 - 2187 (2011)
Vilsmeier-Haack (VH) acetylation reactions with benzaldehydes or acetophenones in MeCN followed second-order kinetics and afforded acetyl derivatives under kinetic conditions, irrespective of the nature of the oxychloride (SOCl2 or POCl3/
Acetamide/SO2Cl2 as an efficient reagent for Friedel-Craft's acylation of aromatic compounds under ultrasonic and microwave conditions
Satish Kumar, Mukka,Chinna Rajanna, Kamatala,Venkanna, Purugula,Venkateswarlu, Marri
, p. 1756 - 1759 (2014/03/21)
Acetamide/SO2Cl2 reagent has been developed for effective Friedel-Craft's acylation of aromatic compounds. Acylation of aromatic compounds with acetamide/SO2Cl2 was much more effective and faster than analogous (acetamide/SOCl2) and (acetamide/POCl 3) reagents even under conventional conditions. However, microwave and ultrasonic assisted reactions afforded high yields of products in very short reaction times (30-40 min under sonication and 3-4 min under microwave assisted conditions).
Synthesis of 2,3-disubstituted-6-chromones of potential medicinal interest
Singh, O. V.,Sangeeta,Khanna, M. S.,Garg, C. P.,Kapoor, R. P.,et al.
, p. 1241 - 1248 (2007/10/02)
The title compounds (12-19) have been synthesized by the condensation of 2,3-disubstituted-6-chromones (8-11) with hydrazine hydrate in the presence of formic or acetic acid.Their structures have been elucidated on the basis o