106635-87-4 Usage
Molecular structure
A complex molecule with an isoindole-1,3(2H)-dione core, a pentyl chain, and a quinoline ring with multiple substituents.
Isoindole-1,3(2H)-dione core
The central structure of the compound, providing stability and a foundation for attaching other functional groups.
Quinoline ring
A heterocyclic aromatic ring system with a nitrogen atom in the 1, 4 position, contributing to the compound's aromaticity and potential pharmacological activity.
Dimethoxy substituents
Two methoxy groups (-OCH3) attached to the quinoline ring, which may influence the compound's solubility, polarity, and interaction with other molecules.
Methyl substituent
A single carbon atom with three hydrogen atoms (-CH3) attached to the quinoline ring, further affecting the compound's properties and potential applications.
Trifluoromethylphenoxy group
A phenoxy group (-OPh) with a trifluoromethyl substituent (-CF3) attached to the quinoline ring, which may contribute to the compound's lipophilicity and potential pharmacokinetic properties.
Potential pharmacological or biological activities
The compound may exhibit biological or pharmacological effects, but further research and testing are needed to determine its specific properties and applications.
Require further research and testing
Due to the complexity of the molecular structure and the presence of multiple functional groups, additional studies are necessary to fully understand the compound's properties and potential uses.
Check Digit Verification of cas no
The CAS Registry Mumber 106635-87-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,6,6,3 and 5 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 106635-87:
(8*1)+(7*0)+(6*6)+(5*6)+(4*3)+(3*5)+(2*8)+(1*7)=124
124 % 10 = 4
So 106635-87-4 is a valid CAS Registry Number.
106635-87-4Relevant articles and documents
PROCESS FOR THE PREPARATION OF QUINOLINE DERIVATIVES
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Page/Page column 7-8, (2010/02/07)
The invention relates to a process for the preparation of certain quinoline derivatives, in particular, 8-[(4-amino-1-methylbutyl)amino]-2,6-dimethoxy-4-methyl-5-(3-trifluoromethylphenoxy)quinoline succinate.
Antimalarials. 16. Synthesis of 2-substituted analogues of 8-[(4-amino-1-methylbutyl)amino]-6-methoxy-4-methyl-5-[3- (trifluoromethyl)phenoxy]quinoline as candidate antimalarials
LaMontagne,Blumbergs,Smith
, p. 1728 - 1732 (2007/10/02)
A series of 2-substituted analogues of the exceptional drug 8-[(4-amino-1-methylbutyl)amino]-6-methoxy-4-methyl-5-[3- (trifluoromethyl)phenoxy]quinoline (I) were prepared and evaluated for both suppressive and prophylactic antimalarial activity. The preparation of analogues of compound I was of interest due to the high level of both blood and tissue schizonticidal activity demonstrated by this compound. One analogue, 8a, was found to be both more active and less toxic than the parent compound I. In addition, three analogues of example 8a were prepared. Although two of the three analogues showed significant antimalarial activity, both were inferior to compound 8a.
