106636-96-8

Basic information

• Product Name: 1,2,3-Triazine, 5-phenyl-
• CAS NO: 106636-96-8
• Molecular Formula: C9H7N3
• Molecular Weight: 157.175
• Mol File: 106636-96-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,2,3-Triazine, 5-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3-Triazine, 5-phenyl-(106636-96-8)
• EPA Substance Registry System: 1,2,3-Triazine, 5-phenyl-(106636-96-8)

Safety Data

• Hazardous Substances Data: 106636-96-8(Hazardous Substances Data)

Usage

Chemical class

Triazine compounds

Structure

Triazine ring with a phenyl group attached to the 5-position

Applications

a. Pharmaceutical industry
b. Antitumor and antimalarial activity
c. Dyes, pigments, and fluorescent compounds development

Versatility

Building block for the synthesis of various organic molecules and materials

Functional groups

Unique structure and functional groups contribute to its wide range of applications

Upstream product

• 10199-68-5 4-phenyl-1H-pyrazole 
• 919802-97-4 4-phenyl-1-trityl-1H-pyrazole 
• 99939-04-5 4-Phenyl-1H-pyrazol-1-amin 
• 289-96-3 1,2,3-triazine 
• 101219-11-8 5-phenyl-2,5-dihydro-1,2,3-triazine 

Downstream Products

• 101161-85-7 6,7-dihydro-3-phenyl-5H-1-pyrindine 
• 10198-81-9 5-phenyl-2-(pyridin-2-yl)pyrimidine 
• 101161-83-5 3-phenyl-5,6,7,8-tetrahydroquinoline 
• 1318759-80-6 2-dibenzylamino-3-methyl-5-phenylpyridine 
• 136364-30-2 2-ethoxy-5-phenylpyridine 
• 34771-47-6 2-methyl-5-phenylpyrimidine 
• 1318759-77-1 2-diethylamino-3-methyl-5-phenylpyridine 
• 29134-16-5 2,5-diphenylpyrimidine 
• 31408-23-8 5-phenyl-pyrimidin-2-ylamine 
• 57623-09-3 3-Imino-2-phenyl-1-propanal 
• 4432-64-8 hydroxymethylenephenylacetaldehyde 

Relevant articles and documents

Inverse electron demand diels-alder reactions of 1,2,3-triazines: Pronounced substituent effects on reactivity and cycloaddition scope

A systematic study of the inverse electron demand Diels-Alder reactions of 1,2,3-triazines is disclosed, including an examination of the impact of a C5 substituent. Such substituents were found to exhibit a remarkable impact on the cycloaddition reactivity of the 1,2,3-triazine without altering, and perhaps even enhancing, the intrinsic cycloaddition regioselectivity. The study revealed not only that the reactivity may be predictably modulated by a C5 substituent (R = CO2Me > Ph > H) but also that the impact is of a magnitude to convert 1,2,3-triazine (1) and its modest cycloaddition scope into a heterocyclic azadiene system with a reaction scope that portends extensive synthetic utility, expanding the range of participating dienophiles. Significantly, the studies define a now powerful additional heterocyclic azadiene, complementary to the isomeric 1,2,4-triazines and 1,3,5-triazines, capable of dependable participation in inverse electron demand Diels-Alder reactions, extending the number of complementary heterocyclic ring systems accessible with implementation of the methodology.

THE REACTIVITY OF MONOCYCLIC 1,2,3-TRIAZINE

The reactivity of unsubstituted 1,2,3-triazine was investigated using various nucleophilic and electrophilic reagents, molecular orbital calculations, and low temperature nmr measurements.