4432-64-8

Basic information

• Product Name: 1-(2-AMINOETHYL)-2-IMIDAZOLIDONE
• Synonyms: CHEMBRDG-BB 4005390;BUTTPARK 52\06-90;1-(BETA-AMINOETHYL)-2-IMIDAZOLIDONE;1-(2-AMINOETHYL)-2-IMIDAZOLIDINONE;1-(2-AMINOETHYL)-2-IMIDAZOLIDONE;(Z)-3-HYDROXY-2-PHENYLPROPENAL;1-(2-Aminoethyl)-2-imidazolidone ,97%
• CAS NO: 4432-64-8
• Molecular Formula: C₉H₈O₂
• Molecular Weight: 129.16
• Mol File: 4432-64-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 138-140°C/0.15mm
• Flash Point: 173.4°C
• Appearance: /
• Density: 1.137g/cm³
• CAS DataBase Reference: 1-(2-AMINOETHYL)-2-IMIDAZOLIDONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-AMINOETHYL)-2-IMIDAZOLIDONE(4432-64-8)
• EPA Substance Registry System: 1-(2-AMINOETHYL)-2-IMIDAZOLIDONE(4432-64-8)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 4432-64-8(Hazardous Substances Data)

Usage

General Description

1-(2-aminoethyl)-2-imidazolidinone, also known as aminoethylimidazolidinone, is a water-soluble cosmetic ingredient that is commonly used as a cosmetic preservative due to its broad-spectrum antimicrobial and anti-fungal properties. It is classified as a cyclic urea and is considered to be a safe and effective alternative to traditional preservatives such as parabens and formaldehyde-releasing agents. It is also used in haircare and skincare products as a conditioning agent, emollient, and viscosity controlling agent. Additionally, it has been found to be non-irritating and non-sensitizing, making it suitable for use in a wide range of cosmetics and personal care products.

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Relevant articles and documents

Probing the Scope of the Amidine–1,2,3-triazine Cycloaddition as a Prospective Click Ligation Method

Despite recent achievements in the development of chemical reactions enabling selective modification of complex biomolecules, the demand for fast and efficient methodologies that allow the attachment of various functional groups to these systems is the subject of intense research. Here, we report on the study of the amidine–1,2,3-triazine cycloaddition reaction, which has the potential to address many of the challenges associated with the development of such chemistry. We describe an optimized protocol leading to the in situ formation of free amidine bases, which directly react in the cycloaddition reaction with 1,2,3-triazines. Our kinetic studies reveal the structural features determining the reaction rates. Finally, we show that the amidine–1,2,3-triazine cycloaddition is extraordinarily selective and orthogonal to other popular ligation reactions. The pros and cons of the methodology are presented.

Malonaldehyde Derivatives: A General One- or Two-Step Synthesis from Substituted Acetic Acids

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