106665-46-7

Upstream product

• 98-88-4 benzoyl chloride 
• 19186-33-5 aristeromycin 
• 188118-64-1 Acetic acid (1S,4R)-4-(6-benzoylamino-purin-9-yl)-cyclopent-2-enylmethyl ester 
• 178456-34-3 (1R,2R)-2-acetoxy-1-(acetoxymethyl)-3-cyclopentene 
• 160154-62-1 (S)-2-Acetoxy-propionic acid (3S,3aS,6aR)-2-oxo-3,3a,4,6a-tetrahydro-2H-cyclopenta[b]furan-3-yl ester 
• 143395-28-2 (1R,5R)-5-hydroxymethyl-2-cyclopenten-1-ol 
• 188118-78-7 N-[9-((1R,4S)-4-Hydroxymethyl-cyclopent-2-enyl)-9H-purin-6-yl]-benzamide 

Downstream Products

• 19186-33-5 aristeromycin 

Relevant academic research and scientific papers

MODIFIED CYCLIC DINUCLEOSIDE COMPOUNDS AS STING MODULATORS

Provided herein are compounds of Formula (I), Formula (II) and/or Formula (III), or pharmaceutically acceptable salts of any of the foregoing, pharmaceutical compositions that include a compound described herein (including pharmaceutically acceptable salt

CYCLIC DI-NUCLEOTIDES AS MODULATORS OF STING

A compound of formula (I) or a pharmaceutically acceptable salt and tautomers thereof, compositions, combinations and medicaments containing said compounds and processes for their preparation. The invention also relates to the use of said compounds, combinations, compositions and medicaments, in the treatment of diseases and conditions in which modulation of STING (Stimulator of Interferon Genes) is beneficial, for example inflammation, allergic and autoimmune diseases, infectious diseases, cancer and as vaccine adjuvants

An expeditious route to carbocyclic nucleosides: (-)-Aristeromycin and (-)-carbodine

The readily available bicyclic lactone (-)-1 was transformed into diacetate (-)-2 which served in an expeditious route to (-)-aristeromycin (3a) and (-)-carbodine (3b) in acceptable yields.