106693-45-2Relevant academic research and scientific papers
The effects of the carbonyl group in the cyclization of 1-hexenyl radicals
Serra,Da Silva Correa,Do Vale
, p. 9463 - 9488 (2007/10/02)
The radical chain cyclization of allyl ether derivatives promoted by tosyl halides and light is suppressed by the presence of one carbonyl group conjugated with the double bond (acrylic double bond).
1,3-DIPOLAR CYCLOADDITION REACTIONS OF PYRAZOLIDINIUM YLIDES WITH VINYL SULFONES. A REGIOSELECTIVE SYNTHESIS OF BICYCLIC PYRAZOLIDINONE ANTIBACTERIAL AGENTS
Jungheim, Louis N.,Barnett, Charles J.,Gray, Joseph E.,Horcher, Linus H.,Shepherd, Timothy A.,Sigmund, Sandra K.
, p. 3119 - 3126 (2007/10/02)
The 1,3-dipolar cycloaddition reaction of pyrazolidinium ylide 1 with substituted vinyl sulfones 5 was studied.Elimination of benzenesulfinic acid from the resulting cycloadducts gave rise to bicyclic pyrazolidinones 3.The (E)-olefin isomers were found to undergo cycloaddition in a highly regioselective fashion.These pyrazolidinones 3 represent the nuclei of an exciting new class of potent antibacterial agents that mimic β-lactams.
