1067-90-9

Basic information

• Product Name: 3-Oxobutylphosphonic acid diethyl ester
• Synonyms: (3-Oxobutyl)phosphonic acid diethyl ester;3-Oxobutylphosphonic acid diethyl ester;Diethyl (3-oxobutyl)phosphonate
• CAS NO: 1067-90-9
• Molecular Formula: C₈H₁₇O₄P
• Molecular Weight: 208.1919
• Mol File: 1067-90-9.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 292.1°Cat760mmHg
• Flash Point: 144.4°C
• Appearance: /
• Density: 1.069g/cm³
• Vapor Pressure: 0.00187mmHg at 25°C
• Refractive Index: 1.422
• CAS DataBase Reference: 3-Oxobutylphosphonic acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Oxobutylphosphonic acid diethyl ester(1067-90-9)
• EPA Substance Registry System: 3-Oxobutylphosphonic acid diethyl ester(1067-90-9)

Safety Data

• Hazardous Substances Data: 1067-90-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H17O4P/c1-4-11-13(10,12-5-2)7-6-8(3)9/h4-7H2,1-3H3

Upstream product

• 3299-38-5 4-(diethylamino)butan-2-one 
• 64-19-7 acetic acid 
• 122-52-1 triethyl phosphite 
• 131490-60-3 2,2,2-triethoxy-2,2-dihydro-5-methyl-1,2λ⁵-oxaphospholene 
• 103-71-9 phenyl isocyanate 
• 2493-02-9 4-bromophenyl isocyanate 
• 682-34-8 crotyl phosphonate de diethyle 
• 1067-71-6 Diethyl (2-oxopropyl)phosphonate 
• 75-11-6 diiodomethane 
• 78-94-4 methyl vinyl ketone 
• 762-04-9 phosphonic acid diethyl ester 
• 762-04-9 Diethyl phosphonate 
• 70519-81-2 (3-Chloro-but-3-enyl)-phosphonic acid diethyl ester 
• 1081-94-3 [2-(2-methyl-[1,3]dioxolan-2-yl)-ethyl]-phosphonic acid diethyl ester 

Relevant articles and documents

A study on the michael addition of dialkylphosphites to methylvinylketone

The addition of dialkylphosphites to methylvinylketone giving dialkyl-3-oxobutyiphosphonates was studied applying different reagents, such as NaOR/ROH, NaOH/H2O under PTC, DBU, and R3Al (R = Me, Et) under different conditions to find

Metallo-phosphorylation of olefins: Reaction of diethyl chlorophosphate with Zirconocene-ethylene complex

Zirconocene-ethylene complex Cp2Zr (CH2 = CH2) reacted with chlorophosphate to form zircono-ethylphosphonate, which could be converted into various functionalized ethylphosphonates.

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Cyclopropanation of 1,2-dibromoethylphosphonate: A synthesis of β-aminocyclopropylphosphonic acid and derivatives

Diethyl (1,2-dibromoethyl)phosphonate was found to undergo cyclopropanation with nitromethane in good yield. The resulting trans β-nitrocyclopropylphosphonate was converted to the trans N-protected aminocyclopropylphosphonate through a reduction-protection sequence. Subsequent hydrolysis gave the free β-aminocyclopropylphosphonic acid without any formation of ring-opening byproduct. Cyclopropanation of 1,2-dibromoethylphosphonates with nitroalkanes and their reduction are also discussed.

A green procedure for the regio- and chemoselective hydrophosphonylation of unsaturated systems using CaO under solventless conditions

Diethyl phosphite and diphenylphosphine add to a series of unsaturated derivatives using environmentally-friendly calcium oxide as a basic promoter under solventless conditions at room temperature. The corresponding adducts are obtained in a totally regio