106782-89-2

Basic information

• Product Name: N-(3-chlorobenzoyl)saccharin
• Synonyms: N-(3-chlorobenzoyl)saccharin
• CAS NO: 106782-89-2
• Molecular Weight: 321.741
• Mol File: 106782-89-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(3-chlorobenzoyl)saccharin(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-chlorobenzoyl)saccharin(106782-89-2)
• EPA Substance Registry System: N-(3-chlorobenzoyl)saccharin(106782-89-2)

Safety Data

• Hazardous Substances Data: 106782-89-2(Hazardous Substances Data)

Upstream product

• 618-46-2 m-Chlorobenzoyl chloride 
• 81-07-2 saccharin 

Downstream Products

• 211985-77-2 (3-chlorophenyl)(cyclohexyl)methanone 

Relevant articles and documents

Nickel-Mediated Photoreductive Cross Coupling of Carboxylic Acid Derivatives for Ketone Synthesis**

A simple visible light photochemical, nickel-catalyzed synthesis of ketones from carboxylic acid-derived precursors is presented. Hantzsch ester (HE) functions as a cheap, green and strong photoreductant to facilitate radical generation and also engages in the Ni-catalytic cycle to restore the reactive species. With this dual role, HE allows for the coupling of a large variety of radicals (1°,2°, benzylic, α-oxy & α-amino) with aroyl and alkanoyl moieties, a new feature in reactions of this type. With both precursors deriving from abundant carboxylic acids, this protocol is a welcome addition to the organic chemistry toolbox. The reaction proceeds under mild conditions without the need for toxic metal reagents or bases and shows a wide scope, including pharmaceuticals and complex molecular architectures.