106787-40-0Relevant academic research and scientific papers
N-sulfonyl-and N-phosphorylbenzimidoylphosphonates
Kolotilo,Sinitsa,Rassukanaya,Onys'ko
, p. 1210 - 1218 (2008/02/03)
A procedure for preparing N-sulfonyl-and N- phosphorylbenzimidoylphosphonates by oxidation of the corresponding α-(sulfonylamino)-and α-(phosphorylamino)benzylphosphonates was developed. The σ constants of imidoylphosphonate groups were evaluated by 19F NMR spectroscopy, and specific features of their electronic effects were considered. The reactions of the imidoylphosphonates obtained with O-, S-, P-, and N-nucleophiles were studied. The phosphonate-phosphoramidate rearrangement of α-aminobenzylidene-bisphosphonates was found. Nauka/Interperiodica 2006.
Studies on organophosphorus compounds XLVII: Acetyl chloride - A versatile reagent for the synthesis of 1-aminoalkyl- and amino(aryl)methylphosphonic acid derivatives
Yuan,Chen,Wang
, p. 490 - 493 (2007/10/02)
Acetyl chloride is used successfully in the synthesis of 1-aminoalkyl- and amino(aryl)methylphosphonic acid derivatives by a three-component condensation reaction involving diethyl phosphoramidate, aldehydes and diphenyl phosphite. Furthermore, in the reaction of benzyl carbamate, aldehydes and phosphorus(III) chloride, acetyl chloride facilates the formation of alkyl hydrogen 1-(benzyloxycahronylamino)alkylphosphonates or aryl(benzyloxycarbonylamino)methylphosphonates, key intermediates in the synthesis of phosphonopeptide with a P-N bond. In comparison with other methods, the present variation affords wider scope of application including the use of some aliphatic aldehydes, fair yields and mild reaction conditions.
Studies on Organophosphorus Compounds XXVIII. An Improved Synthetic Route to 1-Amino-Substituted Benzyl Phosphonic and -Phosphinic Acids
Yuan, Chengye,Qi, Youmao
, p. 472 - 474 (2007/10/02)
An improved method for the synthesis of 1-aminosubstituted benzyl phosphonic and -phosphinic acids under mild conditions is described.It consists of the reaction of diphenoxy chlorophosphine (1) or dichlorophenylphosphine (6) with substituted benzaldehyde
