106792-41-0

Basic information

• Product Name: 6-(TERT-BUTYLDIMETHYLSILYLOXY)-INDOLE
• Synonyms: 6-(TERT-BUTYLDIMETHYLSILYLOXY)-INDOLE;6-[(tert-Butyldimethylsilyl)oxy]-1H-indole
• CAS NO: 106792-41-0
• Molecular Formula: C₁₄H₂₁NOSi
• Molecular Weight: 247.41
• Mol File: 106792-41-0.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 318.8±15.0 °C(Predicted)
• Appearance: /
• Density: 1.013±0.06 g/cm3(Predicted)
• PKA: 17.26±0.30(Predicted)
• CAS DataBase Reference: 6-(TERT-BUTYLDIMETHYLSILYLOXY)-INDOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(TERT-BUTYLDIMETHYLSILYLOXY)-INDOLE(106792-41-0)
• EPA Substance Registry System: 6-(TERT-BUTYLDIMETHYLSILYLOXY)-INDOLE(106792-41-0)

Safety Data

• Hazardous Substances Data: 106792-41-0(Hazardous Substances Data)

Upstream product

• 2380-86-1 6-hydroxy-1H-indole 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 15903-94-3 6-benzyloxy-1H-indole 
• 3189-13-7 6-methoxylindole 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 753488-91-4 [6-(tert-butyl-dimethyl-silanyloxy)-1H-indol-3-yl]-(3,4,5-trimethoxy-phenyl)-methanone 
• 870098-73-0 6-(tert-butyldimethylsiloxymethyl)-2-[6-(4-hydroxy-3,5-dimethyl-phenyl)-3-methoxy-pyridazin-4-yl]-indole-1-carboxylic acid tert-butyl ester 
• 1428972-79-5 1-(6-((tert-butyldimethylsilyl)oxy)-1H-indol-3-yl)-2-chloro-2-phenylethanone 
• 1428969-27-0 1-(6-hydroxy-1H-indol-3-yl)-2-((3-methoxyphenyl)amino)-2-phenylethanone 
• 1428972-80-8 1-(6-((tert-butyldimethylsilyl)oxy)-1H-indol-3-yl)-2-((3-methoxyphenyl)amino)-2-phenylethanone 
• 848357-99-3 6-(tert-butyldimethylsilanyloxy)indole-1-carboxylic acid tert-butyl ester 2-boronic acid 
• 854638-56-5 6-(tert-butyldimethylsilanyloxy)indole-1-carboxylic acid tert-butyl ester 
• 1310716-96-1 C₂₇H₂₉NO₃Si 
• 1207869-48-4 C₂₁H₁₅NO₃ 
• 613679-62-2 BPR₀L₀₈₂ 

Relevant articles and documents

VIRAL REPLICATION INHIBITORS

The present invention relates to a series of novel compounds, methods to prevent or treat viral infections in animals by using the novel compounds and to said novel compounds for use as a medicine, more preferably for use as a medicine to treat or prevent viral infections, particularly infections with RNA viruses, more particularly infections with viruses belonging to the family of the Flaviviridae, and yet more particularly infections with the Dengue virus. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the novel compounds, to the compositions or preparations for use as a medicine, more preferably for the prevention or treatment of viral infections. The invention also relates to processes for preparation of the compounds.

Novel pyridazinone derivatives as inhibitors of CDK2

The present invention relates to compounds according to the general formula (I), with the definitions of the substituents X, R1 and R2 given below in the text, as well as their physiologically acceptable salts, methods for producing these compounds and their use as pharmaceuticals. These compounds are kinase inhibitors, in particular inhibitors of the kinase CDK2 (cyclin-dependent kinase 2)

Novel organophosphorus derivatives of indazoles and use thereof as medicinal products

The present invention relates in particular to novel chemical compounds, particularly to novel organophosphorus derivatives of indazoles, to the compositions containing them, and to the use thereof as medicinal products for treating cancers.