106795-52-2Relevant articles and documents
Borane-Catalyzed Synthesis of Quinolines Bearing Tetrasubstituted Stereocenters by Hydride Abstraction-Induced Electrocyclization
Maier, Alexander F. G.,Tussing, Sebastian,Zhu, Hui,Wicker, Garrit,Tzvetkova, Pavleta,Fl?rke, Ulrich,Daniliuc, Constantin G.,Grimme, Stefan,Paradies, Jan
supporting information, p. 16287 - 16291 (2018/10/15)
The borane-catalyzed synthesis of quinoline derivatives bearing tetrasubstituted stereocenters from vinyl anilines has been developed. Mechanistic studies and quantum-mechanical investigations support the hydride abstraction/electrocyclization/hydride add
PHARMACEUTICAL COMBINATIONS FOR THE TREATMENT OF RESPIRATORY DISEASES
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Page/Page column 30, (2008/06/13)
The present invention relates to new pharmaceutical combinations which contain in addition to one or more, preferably one compound of general formula 1 wherein the groups R1, R2 and R3 may have the meanings given in the cl
POWDER FORMULATIONS FOR INHALATION CONTAINING ENANTIOMERICALLY PURE BETA-AGONISTS
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Page/Page column 30, (2008/06/13)
The present invention relates to powder formulations for inhalation containing enantiomerically pure compounds of general Formula (I) wherein the groups R1, R2 and R3 may have the meanings indicated in the claims and in th
ENANTIOMERICALLY PURE BETA AGONISTS, MANUFACTURING AND USE THEREOF
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Page/Page column 9, (2008/06/13)
The present invention relates to enantiomerically pure compounds of formula 1 wherein the groups R1, R2, R3, m and Ym? may have the meanings given in the claims and specification, processes for preparing them an
Novel combinations of medicaments for the treatment of respiratory diseases containing long-acting beta-agonists and at least one additional active ingredient
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Page/Page column 43, (2010/11/25)
Disclosed are medicament combinations which contain in addition to one or more, preferably one, compound of general formula 1 wherein the groups X, Ra, Rb, R1, R1′, R2, R2′, R2″,
NEW PHARMACEUTICALLY-ACTIVE COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES
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Page/Page column 7-8, (2008/06/13)
The present invention relates to the use of the compounds of general formula 1 wherein the groups R1, R2 and R3 may have the meanings specified in the claims and in the description, for preparing a pharmaceutical compositi
NOVEL LONG-WORKING BETA-2-AGONISTS AND USE THEREOF AS MEDICAMENTS
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Page/Page column 37, (2008/06/13)
The invention relates to compounds of formula (1), wherein groups X, Ra, Rb, R1, R1', R2, R2', R2'', R2''', V and n can have the meanings as cited in the claims and in
New long acting beta-2-agonists and their use as medicaments
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Page/Page column 17, (2008/06/13)
The present invention relates to compounds of formula 1 wherein the groups X, Ra, Rb, R1, R1′, R2, R2′, R2″, R2′″, V and n may have the meanings given in the claims an
REACTIONS OF αω-BIS(BROMOMAGNESIO)ALKANES WITH HETEROCYCLIC ANHYDRIDES. A NOVEL SYNTHESIS OF FIVE AND SIX-MEMBERED 1-(o-AMINOPHENYL)CYCLOALKANOLS AND 1-(2'-AMINO-3'-PYRIDINYL)CYCLOALKANOLS
Canonne, P.,Boulanger, R.,Chantegrel, B.
, p. 663 - 668 (2007/10/02)
Isatoic anhydrides and azaisatoic anhydrides are converted by reaction with 1,4-bis(bromomagnesio)butane and 1,5-bis(bromomagnesio)pentane into the corresponding 1-(o-aminophenyl)cycloalkanols and 1-(2'-amino-3'pyridinyl)cycloalcanols.
Two New Oxindole Syntheses
Fleming, Ian,Loreto, Maria Antonietta,Wallace, Ian H.M.,Michael, Joseph P.
, p. 349 - 360 (2007/10/02)
Two oxindole syntheses are described, both starting from ketones, in which the carbonyl carbon becomes C-3 of the oxindole.The first route uses o-lithioformanilide followed by attack with cyanide ion and hydrolysis.The second uses a pinacol-type rearragement (or the γ-silyl alcohol variation) to create the quaternary centre, and involves an intramolecular displacement of fluoride ion from an unactivated benzene ring by an amide nitrogen to complete the lactam ring.The two routes are stereochemically complementary, giving different spiro-oxindoles from norbornanone.
