106841-07-0Relevant academic research and scientific papers
Ruthenium(II)-Catalyzed C?H Chalcogenation of Anilides
Ma, Wenbo,Weng, Zhengyun,Rogge, Torben,Gu, Linghui,Lin, Jiafu,Peng, Ai,Luo, Xiang,Gou, Xiaojun,Ackermann, Lutz
, p. 704 - 710 (2018)
Ruthenium-catalyzed C?H chalcogenations of anilides with readily available diselenides and disulfides have been achieved. Our strategy features ample substrate scope, affording the mono-ortho selenylated and thiolated anilides with complete site selectivity control and high catalytic efficacy. Detailed mechanistic studies provide strong support for a facile base-assisted internal electrophilic substitution (BIES) metalation event. (Figure presented.).
One Pot Sequential Synthesis of N-[2-(Phenylsulfinyl)phenyl]acetamides: A Ring Opening Rearrangement Functionalization (RORF)
Behera, Ahalya,Rakshit, Amitava,Sahoo, Ashish K.,Patel, Bhisma K.
, p. 1154 - 1165 (2018/12/13)
A CuII catalyzed one-pot sequential synthesis of N-[2-(phenylthio)phenyl]acetamides from benzo[d]thiazol-2-amines, iodoarenes and carboxylic acids (RCOOH) has been accomplished via ring opening rearrangement functionalization (RORF). Here, the ring opening is associated with the loss of carbon and nitrogen atoms with concurrent S-arylation and N-acylation leading to ortho-bifunctionalized products. A further sequential addition of tert-butyl hydroperoxide (TBHP) results in the formation of a sulfur oxidized product, N-[2-(phenylsulfinyl)phenyl]acetamide. A plausible mechanism has been proposed for this unprecedented ring opening rearrangement functionalization (RORF).
