1068435-06-2Relevant academic research and scientific papers
Synthesis of DNA strands site-specifically damaged by C8-arylamine purine adducts and effects on various DNA polymerases
Boege, Nicolas,Jacobsen, Maike I.,Szombati, Zita,Baerns, Sabrina,Di Pasquale, Francesca,Marx, Andreas,Meier, Chris
experimental part, p. 11194 - 11208 (2009/11/30)
C8-Arylamine-dG and C8-arylamine-dA adducts have been prepared using palladium cross-coupling chemistry. These adducts were subsequently converted into the corresponding 5′-O-DMTr-C8-arylamine-3′-O-phosphoramidites and then used for the automated synthesi
Synthesis of DNA-oligonucleotides damaged by arylamine-modified 2′-deoxyguanosine
Boege,Szombati,Meier
, p. 705 - 708 (2008/09/17)
C8-Arylamine-dG adducts bearing a labile N-formamidine group at the exocyclic amino function were converted into their corresponding 5′-O-DMTr-3′-O-phosphoramidite-C8-arylamine-dG derivatives. These compounds were used for the automated synthesis of site-
