1068564-70-4Relevant academic research and scientific papers
Synthesis and in vivo evaluation of 4-deoxy-4,4-difluoro-KRN7000
Leung, Leo,Tomassi, Cyrille,Van Beneden, Katrien,Decruy, Tine,Elewaut, Dirk,Elliott, Tim,Al-Shamkhani, Aymen,Ottensmeier, Christian,Van Calenbergh, Serge,Werner, Joern,Williams, Tony,Linclau, Bruno
, p. 4433 - 4436 (2008)
(Chemical Equation) The synthesis of 4-deoxy-4,4-difluoro-KRN7000 starting from phytosphingosine is described. Key steps include a regioselective benzylation of azidophytosphingosine and a deoxofluor-mediated fluorination of the corresponding 4-ketone. Th
