1068635-54-0Relevant academic research and scientific papers
Studies toward the unique pederin family member psymberin: Full structure elucidation, two alternative total syntheses, and analogs
Feng, Yu,Jiang, Xin,De Brabander, Jef K.
supporting information, p. 17083 - 17093 (2013/01/15)
Two synthetic approaches to psymberin have been accomplished. A highly convergent first generation synthesis led to the complete stereochemical assignment and demonstrated that psymberin and irciniastatin A are identical compounds. This synthesis featured
Formal total synthesis of benzylpedamide: The right half of (+)-pederin
Liu, Degang,Xue, Jijun,Xie, Zhixiang,Wei, Liping,Zhang, Xianshu,Li, Ying
scheme or table, p. 1526 - 1528 (2009/04/07)
The right half of (+)-pederin was synthesized through a convenient and efficient asymmetric synthesis in 14 steps with 8.3% overall yield. The key step was an iodine-induced heterocy-clization to construct the pyran ring. The chiral centers were constructed separately via asymmetric allylation, substrate-controlled diastereoselective reactions, and Sharpless asymmetric dihydroxy-lation.
