1068652-75-4Relevant academic research and scientific papers
Enantioselective kinetic resolution of trans-cycloalkane-1,2-diols
Mueller, Christian E.,Wanka, Lukas,Jewell, Kevin,Schreiner, Peter R.
supporting information; experimental part, p. 6180 - 6183 (2009/04/06)
Finally! The title resolution is achieved with a nonnatural, partially rigid, lipophilic tetrapeptide at low catalyst loadings without additional base or cosolvents. The transition-state model (ball-and-stick model in the scheme; C gray, N blue, O red) emphasizes the interplay between hydrogen-bonding and hydrophobic interactions. (Chemical Equation Presented)
