106871-53-8

Upstream product

• 79-37-8 oxalyl dichloride 
• 106-45-6 para-thiocresol 
• 412299-02-6 thiooxalic acid-chloride S-p-tolyl ester 

Downstream Products

• 144-62-7 oxalic acid 
• 106-45-6 para-thiocresol 
• 685903-46-2 S-(p-tolyl) 5-formylfuran-2-carbothioate 
• 57830-63-4 (E)-3-phenylthioacrylic acid S-p-tolyl ester 
• 1259857-10-7 S-(p-tolyl) cyclohexanecarbothioate 
• 18241-65-1 S-(4-methylphenyl) phenylethanethioate 
• 28122-84-1 4-nitrothiobenzoic acid S-p-tolyl ester 

Relevant academic research and scientific papers

Oxomercaptoacetic acid compound preparation method

The invention provides an oxomercaptoacetic acid compound preparation method, which comprises: carrying out condensation on mercaptan or a cysteine polypeptide compound and oxalyl chloride in the presence of an organic solvent (such as diethyl ether) at a

Oxalic Acid Monothioester for Palladium-Catalyzed Decarboxylative Thiocarbonylation and Hydrothiocarbonylation

Oxalic acid monothioester (OAM), an easily accessible and storable reagent, was reported herein as a thioester synthetic equivalent for palladium-catalyzed decarboxylative thiocarbonylation of organohalides and hydrothiocarbonylation of unsaturated carbon-carbon bonds at room temperature with high chemo- and regioselectivity. The reaction is applicable to the synthesis of cysteine-derived thioesters, thus allowing chemical modification of cysteine-containing peptides. Decarboxylation of OAM proceeds through oxidative addition of Pd(0) to the acyl-S bond, which accounts for the very mild reaction conditions.