106877-25-2

Usage

Synonyms

Trifluoromethylbenzene-1,3-diamine

Physical state

Colorless to pale yellow liquid

Melting point

60-62°C

Applications

a. Synthesis of pharmaceuticals and agrochemicals
b. Building block for dyes, pigments, and other organic compounds
c. Key ingredient in specialty polymers and materials with unique thermal and chemical properties

Reactivity

Highly reactive

Safety precautions

Handle with caution in a controlled laboratory setting

Upstream product

• 75-63-8 Bromotrifluoromethane 
• 108-45-2 m-phenylenediamine 
• 1006384-64-0 C₇H₆BrF₃N₂ 

Downstream Products

• 1006384-65-1 C₉H₃F₃N₂S₂ 

Relevant academic research and scientific papers

NEW CHEMICAL COMPOUNDS

The present invention enco mpasses co mpounds o f general formula (1) wherein R1, M1, L1 and Q are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or anomalous cell prolif

Reactions of Trifluoromethyl Bromide and Related Halides: Part 10. Perfluoroalkylation of Aromatic Compounds induced by Sulphur Dioxide Radical Anion Precursors

Perfluoroalkylation of electron-rich aromatic compounds with trifluoromethyl bromide, or long-chain perfluoroalkyl iodides, was performed in the presence of sodium dithionite or zinc-sulphur dioxide.This alkylation occurred at the ortho and para positions relative to the amino or hydroxy substitutent.Pyrroles were perfluoroalkylated regioselectively at the 2-position.This alkylation was interpreted as a radical aromatic substitution; the formation of the perfluoroalkyl radical can be induced by a single-electron transfer from sulphur dioxide radical anion to the perfluoroalkyl halide.