1069092-74-5

Basic information

• Product Name: N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-3-methyl-2-oxo-4-imidazolidinecarboxamide
• Synonyms: N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-3-methyl-2-oxo-4-imidazolidinecarboxamide
• CAS NO: 1069092-74-5
• Molecular Weight: 335.713
• Mol File: 1069092-74-5.mol

Chemical Properties

• CAS DataBase Reference: N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-3-methyl-2-oxo-4-imidazolidinecarboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-3-methyl-2-oxo-4-imidazolidinecarboxamide(1069092-74-5)
• EPA Substance Registry System: N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-3-methyl-2-oxo-4-imidazolidinecarboxamide(1069092-74-5)

Safety Data

• Hazardous Substances Data: 1069092-74-5(Hazardous Substances Data)

Upstream product

• 39226-96-5 2-chloro-3-(trifluoromethyl)benzylamine 
• 845543-47-7 (S)-tert-butyl 3-methyl-2-oxoimidazolidine-4-carboxylate 
• 845543-46-6 (S)-1-benzyl 4-tert-butyl 3-methyl-2-oxoimidazolidine-1,4-dicarboxylate 
• 98649-15-1 1‐benzyl 4‐methyl 3‐methyl‐2‐oxoimidazolidine‐1,4‐dicarboxylate 
• 76453-31-1 methyl 3-methyl-2-oxo-4-imidazolidinecarboxylate 

Relevant articles and documents

IMIDAZOLIDINE CARBOXAMIDE DERIVATIVES AS P2X7 MODULATORS

The present invention relates to a compound of Formula (I) or a pharmaceutically acceptable salt thereof: The compounds or salts modulate P2X7 receptor function and are capable of antagonizing the effects of ATP at the P2X7 receptor (P2X7 receptor antagonists). The invention also provides the use of such compounds or salts, or pharmaceutical compositions thereof, in the treatment or prevention of disorders / diseases mediated by the P2X7 receptor, for example pain, inflammation or a neurodegenerative disease, in particular pain such as inflammatory pain, neuropathic pain or visceral pain.