39226-96-5

Usage

Uses

Used in Pharmaceutical Industry:
2-CHLORO-3-(TRIFLUOROMETHYL)BENZYLAMINE is used as a chemical intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, 2-CHLORO-3-(TRIFLUOROMETHYL)BENZYLAMINE serves as a key intermediate in the production of agrochemicals, aiding in the creation of effective pesticides and other agricultural chemicals.
Used in Organic Synthesis:
2-CHLORO-3-(TRIFLUOROMETHYL)BENZYLAMINE is employed as a building block in organic synthesis, enabling the construction of a wide range of organic compounds for various applications.
Safety Considerations:
Given its classification as a hazardous substance, 2-CHLORO-3-(TRIFLUOROMETHYL)BENZYLAMINE should be handled with caution to prevent inhalation, ingestion, or skin absorption, as it can be harmful. Proper safety measures and equipment are essential when working with this chemical.

Upstream product

• 39959-94-9 2-chloro-3-trifluoromethylbenzamide 
• 391-12-8 7-trifluoromethylisatin 
• 313-12-2 2-amino-3-(trifluoromethyl)benzoic acid 
• 39226-97-6 2-chloro-3-trifluoromethylbenzoic acid 

Downstream Products

• 1001390-78-8 {[2-chloro-3-(trifluoromethyl)phenyl]methyl}formamide 
• 1001389-64-5 N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-1-(1-methylethyl)-5-oxoprolinamide 
• 1001389-72-5 GS⁽⁸²¹⁾K₁₄₆₀ 
• 1001390-13-1 N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-5-oxo-1-(phenylmethyl)-D-prolinamide 
• 1001390-20-0 N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-1-(2,2-dimethylpropyl)-5-oxoprolinamide 
• 1001390-31-3 N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-1-cyclobutyl-5-oxoprolinamide 
• 1001390-37-9 N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-5-oxo-1-(2-pyridinylmethyl)prolinamide 
• 1001390-38-0 N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-5-oxo-1-(3-pyridinylmethyl)prolinamide 
• 1068433-77-1 N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-5-oxo-4-(phenylmethyl)-3-morpholinecarboxamide 
• 1068433-74-8 (R)-N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-3-methyl-2-oxo-1,3-oxazolidine-4-carboxamide 
• 1068433-88-4 (S)-1,1-dimethylethyl [2-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}amino)-1-(hydroxymethyl)-2-oxoethyl]methylcarbamate 
• 1069092-74-5 N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-3-methyl-2-oxo-4-imidazolidinecarboxamide 
• 1069092-77-8 N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-3-methyl-2-oxo-1-(2-pyrimidinyl)-4-imidazolidinecarboxamide 
• 1069100-27-1 N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-3-methyl-2-oxo-1-(3-pyridinyl)-4-imidazolidinecarboxamide 

Relevant academic research and scientific papers

ARYL FLUOROETHYL UREAS ACTING AS ALPHA 2 ADRENERGIC AGENTS

The invention provides well-defined aryl fluoroethyl ureas that are useful as selective alpha2 adrenergic agonists. As such, the compounds described herein are useful in treating a wide variety of disorders associated with modulation of alpha2 adrenergic receptors.

Process for producing trifluoromethylbenzylamines

The present invention relates to a process for producing a trifluoromethylbenzylamine represented by the general formula (1). This process includes the step of reducing an oxime represented by the general formula (2), where R1represents hydrogen atom, a halogen atom selected from the group consisting of fluorine, chlorine, bromine and iodine, or trifluoromethyl group, where R1is defined as above, and R2represents hydrogen atom, an alkyl group or an aralkyl group. With this process, the trifluoromethylbenzylamine can be produced with high selectivity.