1069123-94-9Relevant academic research and scientific papers
Free-Amine-Directed Iridium-Catalyzed C?H Bond Activation and Cyclization of Naphthalen-1-amines with Diazo Compounds Leading to Naphtho[1,8-bc]pyridines
Yan, Kelu,Lin, Yongxue,Kong, Yong,Li, Bin,Wang, Baiquan
, p. 1570 - 1575 (2019)
Iridium-catalyzed C?H activation and cyclization of naphthalen-1-amines with diazo compounds leading to naphtho[1,8-bc]pyridines have been developed. Different from the previous free-amine-directed C?H functionalization with diazo compounds that relied on the coordination of lone pair electrons or in situ formation of imine, this transformation passes through a five-membered iridacycle intermediate containing an N?Ir σ-bond. It offers an alternative approach for the synthesis of useful diverse naphtho[1,8-bc]pyridine derivatives in mild conditions. (Figure presented.).
Synthesis of indoles via domino reaction of N-Aryl amides and ethyl diazoacetate
Cui, Sun-Liang,Wang, Jing,Wang, Yan-Guang
supporting information; scheme or table, p. 13526 - 13527 (2009/02/06)
A general and concise synthesis of functionalized indoles via domino reaction of N-aryl amides and ethyl diazoacetate has been developed. The methodology offers a great potential for the synthesis of biologically active and naturally occurring indole derivatives. Copyright
