1069128-90-0Relevant academic research and scientific papers
One-Pot Enol Silane Formation-Alkylation of Ketones with Propargyl Carboxylates Promoted by Trimethylsilyl Trifluoromethanesulfonate
Downey, C. Wade,Confair, Danielle N.,Liu, Yiqi,Heafner, Elizabeth D.
, p. 12931 - 12938 (2018/10/20)
Ketones readily undergo conversion to enol silanes in the presence of a trialkylamine base and trimethylsilyl trifluoromethanesulfonate (TMSOTf) and add to propargyl cations to yield β-alkynyl ketones. The propargyl cations are generated in the same react
Silver hexafluoroantimonate-catalyzed direct α-alkylation of unactivated ketones
Naveen, Naganaboina,Koppolu, Srinivasa Rao,Balamurugan, Rengarajan
, p. 1463 - 1473 (2015/05/26)
A practically simple and direct α-alkylation of unactivated ketones using benzylic alcohols has been achieved. The in situ formed acetals are the key for the success of the reaction. The catalyst, silver hexafluoroantimonate(V) (AgSbF6) provide
Triflic acid promoted direct α-alkylation of unactivated ketones using benzylic alcohols via in situ formed acetals
Koppolu, Srinivasa Rao,Naveen, Naganaboina,Balamurugan, Rengarajan
, p. 6069 - 6078 (2014/07/21)
Direct α-alkylation of unactivated ketones using benzylic alcohols as electrophiles has been achieved at room temperature. This reaction takes place via in situ formed acetal using triflic acid and trimethyl orthoformate. It is believed that methyl vinyl
Bifunctional titanocene catalysis in multicomponent couplings: A convergent assembly of β-alkynyl Ketones
Campos, Catherine A.,Gianino, Joseph B.,Ashfeld, Brandon L.
supporting information, p. 2656 - 2659 (2013/07/26)
Herein is described a titanium-catalyzed three-component coupling to assemble β-alkynyl ketones in a single operation. Treatment of an aryl aldehyde with an acetylide and silyl enol ether in the presence of a bifunctional titanocene catalyst enables the highly convergent assembly of β-alkynyl ketones in good to excellent yields.
Rhenium-catalyzed coupling of 2-propynyl alcohols and several nucleophiles via dehydration
Kuninobu, Yoichiro,Ueda, Hirokazu,Takai, Kazuhiko
, p. 878 - 879 (2008/12/22)
Treatment of 2-propynyl alcohols with several nucleophiles in the presence of a catalytic amount of a rhenium complex, [ReBr(CO)3(thf)] 2, gave coupling products via dehydration. In these reactions, C-C, C-O, and C-S bonds can be con
