106981-52-6Relevant articles and documents
Method of preparing 3-cyano-quinolines and intermediates made thereby
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Page/Page column 18; 20; 21, (2010/11/24)
The present invention relates to methods for preparing substituted 3-cyanoquinolines and intermediates obtained by the methods of the present invention. The methods of the invention comprise reacting an N-aryl-2-propanimide with phosphoryl chloride to produce the substituted 3-cyanoquinolines. The methods further comprise reacting arylamines, orthoformates and active methylenes to produce the N-aryl-2-propenamide.