106989-73-5Relevant academic research and scientific papers
A three-component one-pot synthesis of penta-substituted pyrroles via ring opening of α-nitroepoxides
Zhao, Donghong,Zhu, Yue,Guo, Shanshan,Chen, Wenteng,Zhang, Guolin,Yu, Yongping
supporting information, p. 2872 - 2877 (2017/04/26)
A novel and facile one-pot reaction has been developed to synthesize a variety of penta-substituted pyrroles from α-nitroepoxides, primary amines and dialkyl acetylenedicarboxylates under the conditions without catalyst. Furthermore, the controlled experi
Catalytic enantioselective synthesis of α-nitroepoxides via aminolytic kinetic resolution
Meninno, Sara,Napolitano, Loris,Lattanzi, Alessandra
, p. 124 - 128 (2015/02/02)
The first enantioselective synthesis of β-aryl-substituted α-nitroepoxides, exploiting an organocatalyzed aminolytic kinetic resolution (AKR), has been developed. Ring-opening reaction of racemic α-nitroepoxides with aniline in the presence of a readily available Cinchona alkaloid-derived thiourea affords unreacted epoxides in up to 95% ee.
Titanium-mediated reductive cross-coupling reactions of imines with nitriles: An efficient route for the synthesis of α-aminoketones or 1,2-diketones
Chen, Haoyi,Fan, Guoqin,Li, Shi,Mao, Kebin,Liu, Yuanhong
supporting information, p. 1593 - 1596 (2014/03/21)
The reaction of imines with low-valent titanium species, generated in situ by using Ti(OiPr)4/2 c-C5H9MgCl reagent, affords titanium-imine complex, which can couple with nitriles to provide 2,5-diazatitanacyclop
Imidazole Derivatives Useful for Controlling Microbial Growth
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Paragraph 0160; 0161; 0162; 0163, (2013/07/19)
Disclosure is provided for 1,4,5-substituted amino imidazole compounds useful to control microbial growth, compositions including these compounds, devices including these compounds, and methods of using the same.
A modular approach to the synthesis of 1,4,5-substituted-2-aminoimidazoles
Su, Zhaoming,Peng, Lingling,Melander, Christian
, p. 1204 - 1206 (2012/03/27)
Diversified 1,4,5-substituted-2-aminoimidazoles were rapidly assembled via sequential N-H insertion and Grignard addition to α-diazoesters. Lead compounds were identified as antibiotics against Gram-positive bacteria with an MIC value as low as 2 μg/mL.
Electroreductive Coupling of Aromatic Imines with Electrophiles in the Presence of Chlorotrimethylsilane
Shono, Tatsuya,Kise, Naoki,Kunimi, Nobutaka,Nomura, Ryoji
, p. 2191 - 2194 (2007/10/02)
Electroreduction of aromatic imines in the presence of electrophiles gave the corresponding inter- and intramolecular coupling products when the reaction was carried out with the use of chlorotrimethylsilane (CTMS) as the trapping agent of an anion interm
