32142-34-0

Upstream product

• 2114-00-3 2-bromo-1-phenyl-1-propanone 
• 62-53-3 aniline 
• 5650-44-2 methcathinone 
• 1798-60-3 (R)-1-hydroxy-1-phenyl-2-propanone 
• 579-07-7 1-Phenylpropane-1,2-dione 
• 86967-35-3 1-phenyl-2-phenyliminopropan-1-one 
• 29200-10-0 4-methyl-3,5-diphenyl-3H-oxazol-2-one 
• 32142-35-1 (1-methyl-2-oxo-2-phenyl-ethyl)-phenyl-carbamic acid ethyl ester 
• 4187-87-5 1-Phenyl-2-propyn-1-ol 
• 71-43-2 benzene 
• 593-95-3 carbonyl dibromide 
• 51388-20-6 4-benzyloxyaniline hydrochloride 
• 14088-57-4 2-diazo-1-phenyl-1-propanone 
• 64-17-5 ethanol 

Downstream Products

• 106989-73-5 1-phenyl-1-(phenylamino)propan-2-one 
• 10257-92-8 2-phenyl-3-methyl-1H-indole 
• 29200-10-0 4-methyl-3,5-diphenyl-3H-oxazol-2-one 
• 26381-78-2 2,6-dimethyl-5-phenyl-4H-thieno[3,2-b]pyrrole-3-carboxylic acid 
• 1403656-42-7 (E)-2-(3-chlorophenyl)-N-(1-oxo-1-phenylpropan-2-yl)-N-phenyl-N'-tosylacetamidine 
• 1403656-52-9 1,4-diphenyl-3-(3-chlorophenyl)-4-methyl-2-tosylaminopyrrole 
• 91025-67-1 2-methyl-1,3,5-triphenyl-1H-pyrrole 
• 1022-86-2 2-benzoylindole 
• 99334-89-1 1-phenyl-2-(phenylimino)propan-1-one 
• 155699-85-7 (1-Methyl-2-oxo-2-phenyl-ethyl)-phenyl-thiocarbamic acid O-phenyl ester 
• 26309-40-0 2,6-dimethyl-5-phenyl-4H-thieno[3,2-b]pyrrole-3-carboxylic acid ethyl ester 
• 74554-45-3 N-(1-methyl-2-oxo-2-phenyl-ethyl)-benzanilide 

Relevant academic research and scientific papers

Palladium-catalyzed tandem oxidative annulation of α-amino ketones leading to 2-aroylindoles

A simple synthesis of 2-aroylindoles via palladium-catalyzed tandem oxidative annulation directly from α-amino ketones has been developed. In this transformation, two-step reaction including oxidation of α-amino aetones to generate imine intermediates and

Chiral Phosphoric Acid Catalyzed Enantioselective Synthesis of α-Tertiary Amino Ketones from Sulfonium Ylides

Herein we disclose a new catalytic asymmetric approach for the synthesis of chiral α-Amino ketones, which is particularly useful for the less accessible acyclic α-Tertiary cases. By a protonation-Amination sequence, our approach represents a rare asymmetric H-heteroatom bond insertion by α-carbonyl sulfonium ylides, an attractive surrogate of diazocarbonyls. The mild intermolecular C-N bond formation was catalyzed by chiral phosphoric acids with excellent efficiency and enantioselectivity. The products are precursors to other important chiral amine derivatives, including drug molecules and chiral ligands. The enantioselectivity was controlled by dynamic kinetic resolution in the amination step, rather than the initial protonation. This process opens up a new platform for the development of other related insertion reactions.

Synthesis of α-heterosubstituted ketones through sulfur mediated difunctionalization of internal alkynes

Synthesis of α-heterosubstituted ketones was achieved through sulfur mediated difunctionalization of internal alkynes in one pot. The reaction design involves: phenyl substituted internal alkyne attacking triflic anhydride activated diphenyl sulfoxide to

Iron-Catalyzed Methylation Using the Borrowing Hydrogen Approach

A general iron-catalyzed methylation has been developed using methanol as a C1 building block. This borrowing hydrogen approach employs a Kn?lker-type (cyclopentadienone)iron carbonyl complex as catalyst (2 mol %) and exhibits a broad reaction scope. A variety of ketones, indoles, oxindoles, amines, and sulfonamides undergo mono- or dimethylation in excellent isolated yields (>60 examples, 79% average yield).

Highly diastereoselective synthesis of tertiary alcohols via intramolecular Baylis-Hillman reaction using less reactive acrylamides as activated alkenes and ketones as electrophiles

A simple and convenient protocol for highly diastereoselective intramolecular Baylis-Hillman (IBH) reaction of substrates containing less reactive acrylamides as activated alkene and ketones with α-chiral center (racemic) as electrophile components, thus

Br?nsted acid mediated N-O bond cleavage for α-amination of ketones through the aromatic nitroso aldol reaction

A Br?nsted acid mediated N-O bond cleavage for α-amination of ketones has been developed through the nitroso aldol reaction of less-reactive aromatic nitroso compounds and silyl enol ethers having a disilane (-SiMe2TMS) backbone. This transform

Synthesis of Multiple-Substituted Pyrroles via Gold(I)-Catalyzed Hydroamination/Cyclization Cascade

A gold-catalyzed cascade hydroamination/cyclization reaction of α-amino ketones with alkynes to form substituted pyrroles has been developed. The method offers several advantages such as high regioselectivity with the tested cases, wide functional group tolerance, and easily accessible starting materials. The synthetic utility of the obtained pyrrole products was demonstrated by their efficient transformations to 2-vinylated pyrroles via gold-catalyzed intermolecular hydroarylation.

Facile synthesis of 2-methylquinolines from anilines on mesoporous N-doped TiO2 under UV and visible light

Nitrogen-doped TiO2 was synthesized by a simple wet method using a nitrogen precursor hydrazine hydrate and nano TiO2. This photocatalyst was characterized by X-ray diffraction, highresolution transmission electron microscopy, diffused reflectance spectra, photoluminescence, and X-ray photoelectron spectroscopy. XPS analysis indicates the incorporation of anionic nitrogen in TiO2 lattice as O-Ti-N linkage. N2 adsorption-desorpion isotherm indicates the mesoporous nature of N-TiO2 with the surface area 130.0 m2/g. Sizes of N-TiO2 particles are found to be in the range of 5-30 nm by HRTEM images. DRS spectra reveal the extended absorption to the visible range. N-TiO2 is found to be more efficient than Ag-TiO2, Au-TiO2, and Pt-TiO2 in quinaldine synthesis under visible light. Copyright Taylor & Francis Group, LLC.

Asymmetric intermolecular cyclopropanation of alkenes by diazoketones catalyzed by Halterman iron porphyrins

The asymmetric addition of diazoacetophenone to styrene derivatives to give optically active cyclopropyl ketones (ee up to 80%) was carried out using chiral iron porphyrins as homogeneous catalysts. Intermolecular N-H functionalization of anilines by mean

Ruthenium complexes of electronically coupled cyclopentadienone ligands - Catalysts for transformations of propargyl alcohols

A series of donor- and acceptor-substituted ruthenium cyclopentadienone complexes were synthesized and their catalytic activities towards propargyl alcohols focused on amination reactions have been investigated. It is shown that the substituents of the cyclopentadienone ligand determine the mode of activation of propargyl alcohols by these complexes leading to different central intermediates in catalytic cycles. Catalytic transformations of propargyl alcohols to α- or β-amino ketones, enamino ketones, α,β-unsaturated imines, ketones, alkenes and conjugated enynes could be achieved. Wiley-VCH Verlag GmbH & Co. KGaA, 2007.