1070872-52-4Relevant academic research and scientific papers
Catalytic hydroarylation of alkynes with arenes in the presence of FeCl3 and AgOTf
Hashimoto, Takuya,Kutubi, Md. Shahajahan,Izumi, Takayuki,Rahman, Ataur,Kitamura, Tsugio
experimental part, p. 99 - 105 (2011/02/16)
Hydroarylation of propiolic acids with various arenes in TFA proceeded efficiently in the presence of FeCl3/AgOTf catalyst system. In the case of electron-rich arenes, the iron-catalyzed hydroarylation gave cinnamic acids in moderate to high yields. The hydroarylation of phenylacetylene was observed but the catalyst was not effective under the same conditions.
Iron(III)-catalyzed hydroarylation of propiolic acid with activated arenes
Hashimoto, Takuya,Izumi, Takayuki,Kutubi, Md. Shahajahan,Kitamura, Tsugio
scheme or table, p. 761 - 763 (2010/04/05)
FeCl3/AgOTf-catalyzed hydroarylation of propiolic acid with electron-rich arenes such as mesitylene, tetramethylbenzene, and pentamethylbenzene in trifluoroacetic acid proceeded to give 3-arylpropenoic acids in moderate to high yields. The same reactions with anisole and 1,4-dimethoxybenzene afforded double hydroarylation products, 3,3-diarylpropionic acids.
Highly efficient alkyne hydroarylation with chelating dicarbene palladium (II) and platinum(II) complexes
Biffis, Andrea,Tubaro, Cristina,Buscemi, Gabriella,Basato, Marino
scheme or table, p. 189 - 196 (2009/04/07)
We report on a novel reaction protocol for the coupling of arenes with alkynes (the Fujiwara reaction), yielding products of formal trans/hydroarylation of the triple bond. The protocol makes use of a chelating N-heterocyclic dicarbene palladium(II) compl
