1070889-97-2

Upstream product

• 21900-34-5 3-bromo-4-chlorobenzoyl chloride 
• 42860-10-6 3-bromo-4-chlorobenzoic acid 
• 1070892-31-7 4-chloro-N-(2-hydroxy-phenyl)-N-methyl-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzamide 
• 1070892-12-4 3-bromo-4-chloro-N-(2-hydroxy-phenyl)-N-methyl-benzamide 
• 1070892-07-7 3-bromo-4-chloro-N-(2-methoxy-phenyl)-N-methyl-benzamide 
• 1070892-06-6 3-bromo-4-chloro-N-(2-methoxy-phenyl)-benzamide 
• 1070893-06-9 (5-bromo-4-methylpyridin-2-yl)-N-t-butyl carboxylic amide 
• 886364-86-9 5-bromo-4-methyl-pyridine-2-carbonitrile 
• 3430-26-0 2,5-Dibromo-4-methylpyridine 
• 98198-48-2 2-amino-5-bromo-4-methylpyridine 
• 1070889-90-5 4-chloro-3-(6-cyano-4-methyl-pyridin-3-yl)-N-(2-hydroxy-phenyl)-N-methyl-benzamide 
• 627-18-9 1-bromo-3-propanol 

Relevant academic research and scientific papers

GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO

GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure, wherein R1a, R1b, R1c, R1d, R2, R2a, and A are as defined herein, including stereoisomers, esters, solvates and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.