107089-95-2Relevant academic research and scientific papers
Novel Preparation of 1-Aryl-3-(2-hydroxyphenyl)-2-pyrazolin-5-ones and their Conversion into 2-Aryl-4-methyl[1] benzopyrano[4,3-c] pyrazol-3(2H)-ones
Froggett, Jayne A.,Hockley, Michael H.,Titman, Roger B.
, p. 30 - 31 (2007/10/03)
1-Aryl-3-(2-hydroxyphenyl)-2-pyrazolin-5-ones are prepared from 4-hydroxycoumarin and arylhydrazines and then cyclised with triethyl orthoacetate to give 2-aryl-4-methyl[1]benzopyrano[4,3-c]pyrazol-3(2H)-ones.
Tricyclic heteroaromatic systems: Synthesis, [3H]flunitrazepam brain membrane binding inhibition, and structure-activity relationships of 2,3-dihydro-2-aryl-4-R-[1]benzopyrano[4,3-c]pyrazole-3-ones
Colotta,Cecchi,Melani,Palazzino,Filacchioni,Martini,Giannaccini,Lucacchini
, p. 239 - 242 (2007/10/02)
We report the synthesis and binding activity to the central benzodiazepine receptors of some 2,3-dihydro-2-ary-4-R-[1]benzopyrano[4,3-c]pyrazole-3-ones, which are isosteres of the CGS series. Although the compounds of the CGS series are potent ligands of
THE CORRECT SYNTHESIS OF 2,3-DIHYDRO-2-ARYL-4-R-BENZOPYRANOPYRAZOLE-3-ONES.
Colotta, Vittoria,Cecchi, Lucia,Melani, Fabrizio,Palazzino, Giovanna,Filacchioni, Guido
, p. 5165 - 5168 (2007/10/02)
The correct synthesis of the title compounds 1a-b and 2a-b is described.The claimed synthesis of 2a from 2-methyl-3-chromonecarbonitrile is shown not to lead to 2a, as previously reported but to 1,4-dihydro-1-phenyl-3-methylbenzopyranopyrazole-4
Benzopyrans: Part XX - 4-Oxo-4H-benzopyran-3-carbonitrile/Carboxylic Acid: Change of Their Reaction Courses by a Methyl Substituent at 2-Position
Ghosh, Chandra Kanta,Pal, Chandana
, p. 1288 - 1290 (2007/10/02)
2-Methyl-4-oxo-4H-benzopyran-3-carbonitriles (1b) and the corresponding carboxylic acids (2b), unlike their 2-unsubstituted analogues (1a) and (2a), give with phenyl hydrazine the hydrazones (6b) and the pyrazoles (13b), respectively.The hydrazones (6b) have been converted into the benzopyranopyrazoles (8b).
